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个人简介
Dr. Moore’s research at UMMS and HHMI encompassed a broad array of topics related to the role of RNA and RNA-protein (RNP) complexes in gene expression. She is particularly known for her mechanistic and structural analyses of spliceosomes and mRNPs, co-discovery of the exon junction complex (EJC), and studies of intracellular RNA transport and quality control pathways. She was also instrumental in developing multiple enabling technologies for the field, including methods for introducing site-specific modifications into long RNA molecules and single molecule methods for observing the dynamics of RNP complex assembly and disassembly. At Moderna Therapeutics, Moore directs research into novel delivery mechanisms for therapeutic mRNAs and how to increase their functional output and longevity.
研究兴趣
论文共 252 篇作者统计合作学者相似作者
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Alicia A. Bicknell,David W. Reid, Marissa C. Licata, Adriana K. Jones, Yi Min Cheng, Mengying Li,Chiaowen Joyce Hsiao, Christopher S. Pepin,Mihir Metkar,Yevgen Levdansky, Brian R. Fritz, Elizaveta A. Andrianova,
Genome research (2024)
Nature reviews. Drug discoveryno. 1 (2023): 67-83
Zachary T. Rosenkrans,Christopher F. Massey,Ksenija Bernau,Carolina A. Ferreira,Justin J. Jeffery,Jefree J. Schulte,Melissa Moore,Frank Valla, Jeanine M. Batterton, Christopher R. Drake,Alan B. McMillan,Nathan Sandbo,
David Alvarez, Guillemette Masse-Ranson,Saikiran K Sedimbi, Phylicia Wisti, Lisa Rodriguez, Jordan Santana,Taylor Manning, Tim Towner,Ben Geilich,Cosmin Mihai,Ankita Mishra,Sushma Gurumurthy,
biorxiv(2022)
F. Novruzov,A. Aliyev, S. Novruzova, N. Orucova, I. Aliyeva,M. Moore, F. Valla,F. Giammarile,E. Mehdi
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