His area of expertise includes vascular medicine and minimally invasive, catheter-based procedures such as angioplasty, stent grafts, stenting, atherectomy and intravascular ultrasound to treat coronary, carotid, abdominal aortic aneurysms, and peripheral arterial and venous diseases. He is an expert on minimally invasive approaches to reconstruct lower extremity arteries in order to treat critical limb ischemia and prevent amputation. His work in this area has been recognized locally, nationally and internationally. Prior to joining University Hospitals, Dr. Shishehbor directed the Endovascular Program at the Cleveland Clinic from 2009 to May 2017 and trained over 40 interventional fellows and over 400 physicians nationally on advanced techniques for limb salvage.