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个人简介
Murphy studies the genetics of the p53 tumor suppressor protein. Her laboratory focuses on genetic variants of p53 that exist in populations of African-descent (P47S and Y107H) and Ashkenazi Jewish (G334R). Her work seeks to understand the impact of these genetic variants of p53 on cancer risk and the efficacy of cancer therapy. She also seeks to identify personalized medicine approaches for tumors with these variants. Therefore, her work has direct relevance for improving the cancer prognosis and therapy of African and Ashkenazi Jewish Americans. Murphy also studies the cancer-survival protein HSP70. Her lab employs a novel series of HSP70 inhibitors for melanoma and colorectal cancer therapy.
研究兴趣
论文共 218 篇作者统计合作学者相似作者
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Brittany Lipchick,Adam N. Guterres,Hsin-Yi Chen, Delaine M Zundell, Segundo Del Aguila,Patricia I. Reyes-Uribe,Subhasree Basu,Xiangfan Yin,Andrew V. Kossenkov,Yiling Lu,Gordon B. Mills,Qin Liu,
biorxiv(2024)
Cancer Researchno. 6_Supplement (2024): 3025-3025
Connor M Hill,Alexandra Indeglia, Francis Picone,Maureen E Murphy, Cara Cipriano,Robert G Maki,Alessandro Gardini
bioRxiv : the preprint server for biology (2024)
Renyta Moses,Gregory Kelly, Alexandra Indeglia, Sven Miller,John Karanicolas,Maureen Murphy,Kara Maxwell
CANCER RESEARCHno. 7 (2023)
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Abibatou Ndoye, Anna Budina-Kolomets,Curtis H. Kugel,Marie R. Webster,Amanpreet Kaur,Reeti Behera,Vito W. Rebecca, Ling Li,Patricia A. Brafford,Qin Liu,Y.N. Vashisht Gopal,Michael A. Davies,
crossref(2023)
Vito W. Rebecca,Michael C. Nicastri,Noel McLaughlin, Colin Fennelly,Quentin McAfee,Amruta Ronghe, Michel Nofal,Chun-Yan Lim, Eric Witze,Cynthia I. Chude,Gao Zhang,Gretchen M. Alicea,
crossref(2023)
Cancer discoveryno. 5 (2023): 1046-1048
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