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We have recently shown that contrary to common hypotheses, circulating monocytes can efficiently differentiate into Kupffer cells (KCs), the liver-resident macrophages. Using self-generated knock-in mice that allow specific KC depletion, we found that monocytes colonize the KC niche in a single wave upon KC depletion and rapidly differentiate into self-maintaining KCs that are transcriptionally and functionally identical to their embryonic counterparts.
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Marie Laviron,Martin Guilliams
Trends in cancerno. 3 (2024): 175-176
Andrew S Perry, Niran Hadad,Emeli Chatterjee,Maria Jimenez Ramos,Eric Farber-Eger, Rashedeh Roshani, Lindsay K Stolze,Shilin Zhao,Liesbet Martens,Timothy J Kendall,Tinne Thone,Kaushik Amancherla,
medRxiv : the preprint server for health sciences (2024)
Miriam Wöhner, Sarah Brechtelsbauer,Niklas Friedrich, Christof Vorsatz, Johanna Bulang,Chunguang Liang, Lena Schorr, Alain Beschin,Martin Guilliams,Jeffrey Ravetch,Falk Nimmerjahn,Markus Biburger
Cell Reportsno. 2 (2024): 113757-113757
Cell Researchno. 3 (2024): 191-192
medRxiv (Cold Spring Harbor Laboratory) (2023)
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