基本信息
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职业迁徙
个人简介
Professional and research activities
Investigation of relationships between the chemical structure and biological activity of pyrazinecarboxylic acid derivatives as potential antituberculotics and antimycotics. Rational design and synthesis of novel potential therapeutic agents (non-steroidal antileucotrienics). Study of inhibition of photosynthetic electron transport in spinach chloroplasts in substituted amides of pyrazinecarboxylic acid. Design and synthesis of elicitors derived from pyrazine. Synthesis and evaluation of reactivators of inhibited acetylcholinesterase.
Author of 94 original papers (75 in the journals with impact factor), 24 reviews (11 in the journals with impact factor), more than 200 posters and 60 plenary or short lectures at symposia in the Czech Republic and world congresses abroad. Author (2 textbooks, 2 chapters) or co-author of 6 manual scripts and 11 grant projects.
Membership
Czech Pharmaceutical Society (1985-), member of Committee (2005-), vice-president (2011-2014), president (2015-), Section of Synthetic Drugs Committee Chairman (2019–)
Investigation of relationships between the chemical structure and biological activity of pyrazinecarboxylic acid derivatives as potential antituberculotics and antimycotics. Rational design and synthesis of novel potential therapeutic agents (non-steroidal antileucotrienics). Study of inhibition of photosynthetic electron transport in spinach chloroplasts in substituted amides of pyrazinecarboxylic acid. Design and synthesis of elicitors derived from pyrazine. Synthesis and evaluation of reactivators of inhibited acetylcholinesterase.
Author of 94 original papers (75 in the journals with impact factor), 24 reviews (11 in the journals with impact factor), more than 200 posters and 60 plenary or short lectures at symposia in the Czech Republic and world congresses abroad. Author (2 textbooks, 2 chapters) or co-author of 6 manual scripts and 11 grant projects.
Membership
Czech Pharmaceutical Society (1985-), member of Committee (2005-), vice-president (2011-2014), president (2015-), Section of Synthetic Drugs Committee Chairman (2019–)
研究兴趣
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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2024): 116077-116077
ACS infectious diseasesno. 8 (2023): 1674-1674
ACS INFECTIOUS DISEASESno. 8 (2023): 1674-1674
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European journal of medicinal chemistry (2023): 115617
The 8th International Electronic Conference on Medicinal Chemistryno. 133 (2022): 133
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