Mark R. Harpel - Department of Chemical Enzymology, DuPont Pharmaceuticals Company, Experimental Station, PO Box 80400, Wilmington, DE 19880, USA

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BMS-262084, a nonpeptide factor XIa inhibitor: enzyme kinetics, antithrombotic and antihemostatic studies

P. Wong, C. Kettner, W. Schumacher,C. Watson, E. Crain, L. Mersinger,M. Harpel,A. Rendina

EUROPEAN HEART JOURNAL（2010）

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Glutamyl-γ-boronate Inhibitors of Bacterial Glu-tRNAGln Amidotransferase

Carl P. Decicco,David J. Nelson,Ying Luo,Li Shen,Kurumi Y. Horiuchi,Karen M. Amsler,Lorie A. Foster,Susan M. Spitz,Jayson J. Merrill,Christine F. Sizemore,Kelley C. Rogers,Robert A. Copeland,

Bioorganic & Medicinal Chemistry Letters（2010）

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Mutagenesis and mechanism-based inhibition of Streptococcus pyogenes Glu-tRNAGln amidotransferase implicate a serine-based glutaminase site

Mark R. Harpel,Kurumi Y. Horiuchi,Ying Luo,Li Shen,Wenjun Jiang,David J. Nelson,Kelley C. Rogers,Carl P. Decicco,Robert A. Copeland

BIOCHEMISTRY（2002）

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Mechanistic Studies of Reaction Coupling in Glu-tRNA^GlnAmidotransferase

Kurumi Y. Horiuchi,Mark R. Harpel,Li Shen,Ying Luo,Kelley C. Rogers,Robert A. Copeland

BIOCHEMISTRY（2001）

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Glutamyl-gamma-boronate inhibitors of bacterial Glu-tRNA(Gln) amidotransferase

C P Decicco,D J Nelson, Y Luo, L Shen, K Y Horiuchi, K M Amsler, L A Foster, S M Spitz, J J Merrill, C F Sizemore, K C Rogers,R A Copeland,

Bioorganic & medicinal chemistry lettersno. 18 (2001)

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Glutamyl-Gamma-Boronate Inhibitors Of Bacterial Glu-Trna(Gln) Amidotransferase (Vol 11, Pg 2561, 2001)

Cp Decicco,Dj Nelson,Y Luo, L Shen,Ky Horiuchi, Km Amsler, La Foster, Sm Spitz, Jj Merrill,Cf Sizemore, Kc Rogers,Ra Copeland,

BIOORGANIC & MEDICINAL CHEMISTRY LETTERSno. 23 (2001)

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Corrigendum to “Glutamyl-γ-boronate Inhibitors of Bacterial Glu-tRNAGln Amidotransferase” [Bioorg. Med. Chem. Lett. 11 (2001) 2561]

Carl P. Decicco,David J. Nelson,Ying Luo,Li Shen,Kurumi Y. Horiuchi,Karen M. Amsler,Lorie A. Foster,Susan M. Spitz,Jayson J. Merrill,Christine F. Sizemore,Kelley C. Rogers,Robert A. Copeland,

Bioorganic & Medicinal Chemistry Letters（2001）

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Thiolate ligation of the active site iron(II) of isopenicillin N synthase derives from substrate rather than endogenous cysteine: spectroscopic studies of site-specific Cys .fwdarw. Ser mutated enzymes

Allen M. Orville,Victor J. Chen,Aidas Kriauciunas,Mark R. Harpel,Brian G. Fox,Eckard Munck,John D. Lipscomb

BIOCHEMISTRY（1992）

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105

Partial reactions and chemical rescue of site-directed mutants of Rubisco as mechanistic probes

Mark R Harpel,Frank W Larimer,Eva Y H P Lee,Richard J Mural, Harry Smith, T S Soper, F C Hartman

mag（1991）

引用23浏览0引用

Evaluation Of The Roles Of H321 And S368 Of R-Rubrum Ribulose Bisphosphate Carboxylase/Oxygen By Site-Directed Mutagenesis

Mark R Harpel,Frank W Larimer,Richard J Mural

FASEB JOURNAL（1991）

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