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Mark W. Dewhirst, DVM, PhD is the Gustavo S. Montana Professor of Radiation Oncology and Vice Director for Basic Science in the Duke Cancer Institute. Dr. Dewhirst has research interests in tumor hypoxia, angiogenesis, hyperthermia and drug transport. He has spent 30 years studying causes of tumor hypoxia and the use of hyperthermia to treat cancer. In collaboration with Professor David Needham in the Pratt School of Engineering, he has developed a novel thermally sensitive drug carrying liposome that has been successfully translated to human clinical trials. He has utilized the thermal characteristics of this liposome to develop an MR imageable form that can accurately reflect drug concentrations in tumors, which then is related to the extent of anti-tumor effect in pre-clinical models.
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论文共 276 篇作者统计合作学者相似作者
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Ashlyn G Rickard,Dorababu S Sannareddy,Alexandra Bennion,Pranalee Patel,Scott J Sauer,Douglas C Rouse, Samantha Bouchal, Harrison Liu,Mark W Dewhirst,Gregory M Palmer,Gayathri R Devi
Cancersno. 8 (2023)
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Yiting Cao,Pierre Sonveaux,Shanling Liu,Yulin Zhao,Jing Mi, Bryan M. Clary,Chuan-Yuan Li, Christopher D. Kontos,Mark W. Dewhirst
crossref(2023)
CURRENT ONCOLOGYno. 3 (2023): 2751-2760
crossref(2023)
Bin Yan, Huili Wang,Zahid N. Rabbani,Yulin Zhao,Wenrong Li, Yuqing Yuan,Fang Li,Mark W. Dewhirst,Chuan-Yuan Li
crossref(2023)
semanticscholar(2021)
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