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We will do this in collaboration with others worldwide, under the umbrella of the Earth BioGenome Project. Within In ToL we will be generating and analysing reference genomes for the diverse eukaryotic species, in the British Isles with collaborators in the Darwin UK Tree of Life Project. I am excited to be at the centre of this visionary network of genome scientists, biologists, conservationists and bioinformaticians, who are all dedicated to unlocking the secrets of life on earth.
Our planet is experiencing the sixth great extinction, where acceleration of biodiversity loss threatens the health of the ecosystems on which the health of human society depends. In the Tree of Life Programme, we are using genomics to understand the deep roots of biodiversity, delve into the unique biology of threatened organisms, and provide tools for conservation and mitigation of climate change and other threats.
The diversity of life is encoded in genomes. Genomes are much more than strings of chemical letters: they store the instructions for building each organism, and the history of the evolution of the species through deep time. We are lucky to be at a point in the development of genomic and informatic technologies where it is possible to build high-quality, essentially complete chromosomal reference genomes for thousands of species. Where previously a “reference genome” approach was only applied to humans and important model species, we can now extend this approach to all of life. We are therefore planning to sequence many thousands of genomes per year, from animals, plants, fungi and single-celled organisms. These will be released to the global community – to transform the way all of biological science is practiced in the future.
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论文共 438 篇作者统计合作学者相似作者
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Ann M Mc Cartney,Giulio Formenti,Alice Mouton,Diego De Panis,Luisa S Marins,Henrique G Leitao,Genevieve Diedericks, Joseph Kirangwa,Marco Morselli,Judit Salces, Nuria Escudero,Alessio Iannucci,
biorxiv(2024)
MICROBIOLOGY SPECTRUMno. 2 (2024): e0366923-e0366923
Nature Ecology & Evolutionpp.1-14, (2024)
PLOS GENETICSno. 1 (2024): e1011116-e1011116
Wellcome Open Research (2023)
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Joseph Kirangwa,Dominik R Laetsch, Erna King,Lewis Stevens,Mark Blaxter,Oleksandr Holovachov,Philipp Schiffer
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Wellcome Open Research (2023)
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