Marian E. Major - Division of Viral Products, US Food and Drug Administration

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Bio

MARIAN MAJOR, PhD, is currently Chief of the Laboratory of Hepatitis Viruses in the Center for Biologics Research and Evaluation, US Food and Drug Administration. Her email address is marian.major@fda.hhs.gov.

Research Interests

Papers共 68 篇Author StatisticsCo-AuthorSimilar Experts

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Combined Immunization with SARS-CoV-2 Spike and SARS-CoV Nucleocapsid Protects K18-hACE2 Mice but Increases Lung Pathology

Jaekwan Kim,Alla Kachko,Prabhuanand Selvaraj, David Rotstein, Charles Brandon Stauft, Naveen Rajasagi, Yangqing Zhao,Tony Wang,Marian Major

npj Vaccinesno. 1 (2025): 1-12

Cited0Views0WOSNATUREBibtex

Modeling of Randomized Hepatitis C Vaccine Trials: Bridging the Gap Between Controlled Human Infection Models and Real-Word Testing

Mary-Ellen Mackesy-Amiti,Alexander Gutfraind,Eric Tatara,Nicholson T. Collier,Scott J. Cotler,Kimberly Page,Jonathan Ozik,Basmattee Boodram,Marian Major,Harel Dahari

PNAS NEXUSno. 1 (2025)

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OS-063 What Happens to HCV Incidence after WHO Elimination Goal is Met? Agent-based Modeling Predicts Sustained Availability of Direct-Acting Antivirals among People Who Inject Drugs is Required to Prevent Returning to Pre-Elimination Levels

Eric Tatara,Louis Shekhtman,Nicholson Collier,Marian Major,Jonathan Ozik,Basmattee Boodram,Harel Dahari

Journal of Hepatology (2024): S43

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405 Nm Violet-Blue Light Inactivates Hepatitis C Cell Culture Virus (hcvcc) in Ex Vivo Human Platelet Concentrates and Plasma

Joseph W. Jackson,Pravin R. Kaldhone,Caitlin Stewart, John Anderson,Scott Macgregor,Michelle Maclean,Marian Major,Chintamani D. Atreya

SCIENTIFIC REPORTSno. 1 (2024)

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Theoretical Modeling of Hepatitis C Acute Infection in Liver-Humanized Mice Support Pre-Clinical Assessment of Candidate Viruses for Controlled-Human-infection Studies

Zhenzhen Shi,Adquate Mhlanga,Yuji Ishida, Ari Josephson,Nicholson T. Collier,Hiromi Abe-Chayama, Chise Tateno-Mukaidani,Scott J. Cotler,Jonathan Ozik,Marian Major,Jordan J. Feld,Kazuaki Chayama,Harel Dahari

SCIENTIFIC REPORTSno. 1 (2024)

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Distinct Conformations of SARS-CoV-2 Omicron Spike Protein and Its Interaction with ACE2 and Antibody

Myeongsang Lee,Marian Major,Huixiao Hong

International journal of molecular sciences（2023）

Cited6Views0WOSBibtex

Vaccine-associated Respiratory Pathology Correlates with Viral Clearance and Protective Immunity after Immunization with Self-Amplifying RNA Expressing the Spike (S) Protein of SARS-CoV-2 in Mouse Models

Alla Kachko,Prabhuanand Selvaraj,Shufeng Liu, Jaekwan Kim, David Rotstein,Charles B. Stauft,Sylvie Chabot, Naveen Rajasagi,Yangqing Zhao,Tony Wang,Marian Major

Vaccine（2023）

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Assessing the Impact of Hepatitis B Immune Globulin (HBIG) on Responses to Hepatitis B Vaccine During Co-Administration

Iryna Zubkova, Yangqing Zhao, Qingwen Cui,Alla Kachko,Yusra Gimie,Sylvie Chabot,Trudy Murphy,Sarah Schillie,Marian Major

Vaccineno. 4 (2023): 955-964

Cited1Views0WOSBibtex

Modeling Hepatitis C Micro-Elimination among People Who Inject Drugs with Direct-Acting Antivirals in Metropolitan Chicago

Eric Tatara,Alexander Gutfraind,Nicholson T. Collier,Desarae Echevarria,Scott J. Cotler,Marian E. Major,Jonathan Ozik,Harel Dahari,Basmattee Boodram

PLoS ONE（2022）

Cited8Views0WOSBibtex

EnhancedIn VitroandIn VivoPotency of a T Cell Epitope in the Ebola Virus Glycoprotein Following Amino Acid Replacement at HLA-A*02:01 Binding Positions

Sylvie Chabot,Yusra Gimie,Karam Obeid, Jaekwan Kim,Clement A. Meseda,Krishnamurthy Konduru,Gerardo Kaplan,Li Sheng Fowler,Jerry P. Weir,Keith Peden,Marian E. Major

Journal of Virologyno. 18 (2022)

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