基本信息
浏览量:77
职业迁徙
个人简介
My main research interest is in theoretical biochemistry, in particular reaction mechanisms of metalloenzymes. We use the tools of quantum chemistry, mainly hybrid-DFT, to study the reaction mechanism of various metalloenzymes. The emphasis is on systems with redox active transition metals, such as cytochrome c oxidase (CcO) in the respiratory chain and nitric oxide reductase (NOR) involved in the denitrification process in bacteria. In CcO molecular oxygen is reduced to water, and we are studying both the mechanism and energetics for the oxygen reduction process, and the mechanisms for the proton pumping across the membrane, which occurs coupled to the exergonic oxygen reduction. In NOR nitric oxide is reduced to nitrous oxide and water, and we are studying the mechanism and energetics of this reaction, with particular emphasis on comparisons between the two enzymes, CcO and NOR, which belong to the same family of heme-copper oxidases.
研究兴趣
论文共 187 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Journal of Inorganic Biochemistry (2024): 112534-112534
ACS CATALYSISno. 3 (2023): 2025-2038
CHEMICAL SOCIETY REVIEWSno. 20 (2020): 7301-7330
Longfei Yu, Eliza Harris, Dominika Lewicka‐Szczebak, Matti Barthel, Margareta R.A. Blomberg, Stephen J. Harris, Matthew S. Johnson, Moritz F. Lehmann, Jesper Liisberg, Christoph Müller, Nathaniel E. Ostrom, Johan Six,
crossref(2020)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn