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职业迁徙
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Research summary
Every week around 3500 new pieces of research involving animals are published. It is almost impossible for anyone to stay up to date with current knowledge. We have also shown that much of that work is at substantial risk of bias - and the effects observed in animals may be substantially overstated as a consequence.
In our research we are developing tools to provide unbiased summaries of what is already known, including tools to assess whether effects in animals may be overstated. We then use this information to help guide better design of clinical trials testing treatments in humans.
Examples of trials we have helped design using this approach include EuroHYP-1 - a trial of brain cooling in stroke - and MS-SMART, a trial in secondary progressive multiple sclerosis.
Every week around 3500 new pieces of research involving animals are published. It is almost impossible for anyone to stay up to date with current knowledge. We have also shown that much of that work is at substantial risk of bias - and the effects observed in animals may be substantially overstated as a consequence.
In our research we are developing tools to provide unbiased summaries of what is already known, including tools to assess whether effects in animals may be overstated. We then use this information to help guide better design of clinical trials testing treatments in humans.
Examples of trials we have helped design using this approach include EuroHYP-1 - a trial of brain cooling in stroke - and MS-SMART, a trial in secondary progressive multiple sclerosis.
研究兴趣
论文共 273 篇作者统计合作学者相似作者
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Tracey L. Weissgerber,Małgorzata Anna Gazda,Gustav Nilsonne,Gerben ter Riet,Kelly D. Cobey, Julia Prieß-Buchheit, Jorge Noro,Robert Schulz, Joeri K. Tijdink,Evgeny Bobrov, Alexandra Bannach-Brown, Delwen L. Franzen,
The Lancet Regional Health - Europe (2024): 100782
引用0浏览0WOS引用
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The Journal of endocrinologyno. 1 (2023)
Edoardo G Ostinelli,Virginia Chiocchia,Malcolm Macleod,Michael Browning, C J Harmer,Spyridon Siafis, Claire Stansfield, Claire Friedrich, Simonne Wright, Tannatswa Chikaura, Lea Milligan,James Thomas,
Wellcome open research (2023): 425-425
引用1浏览0引用
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NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2023): 105016-105016
Simonne Wright,Toshi A Furukawa,Malcolm Macleod, Simple Ouma,Olufisayo Elugbadebo,Virginia Chiocchia, Claire Friedrich,Edoardo G Ostinelli,Jennifer Potts, Fiona J Ramage,Spyridon Siafis, Claire Stainsfield,
Wellcome open research (2023): 494-494
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MULTIPLE SCLEROSIS JOURNAL (2023): 348-348
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