I am a Veterinarian with Ph.D. in Molecular Immunology. Research in my lab is focused on delineating the role of tumor immune microenvironment in cancer progression and treatment response. Our long term goal is to identify genomic correlates of prognostic and predictive immune biomarkers that reflect differential pre-treatment tumour immune contexture. Identification of these biomarkers will inform decisions for individualized treatment approaches, augment design of novel immunomodulatory therapies and enhance response to conventional chemotherapies.

Research Interests
Research in my lab focuses on anti-tumour immunity and treatment response in ovarian and prostate cancers.

Major themes and areas of research:
Role of Type I Interferon pathways in sensitivity or resistance to chemotherapy in ovarian cancer using cancer cell lines, in vivo mouse models and patient derived material.
Immuno-genomic studies to delineate genetic correlates of intra-tumour immune diversity and association with intrinsic and acquired resistance to therapy.
Role of cancer cell intrinsic genetic events and their association with distinct immune microenvironment states in prostate cancer.
Development of improved non-invasive immune monitoring approaches towards their application as prognostic and predictive indicators for personalized treatment approaches in cancer.