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The main topic of his research is the modulation of inflammation in tissue repair/regeneration, namely through the design of immunomodulatory microenvironments. At i3S he leads the Microenvironments for New Therapies (MiNT) group.
The MiNT Group bioengineers microenvironments to promote tissue repair/regeneration through modulation of the host response. Pivotal in this strategy is the concept that biomaterials can be engineered to drive inflammation towards either pro- or anti-inflammatory microenvironments. This rational has been consistently adopted by the group, with a particular emphasis in spine diseases, namely those affecting bone and the intervertebral disc.
This translational oriented research is founded on more fundamental and well-established contributions of the group to the understanding and modulation of cell-biomaterial interactions, namely on how biomaterials chemistry can be designed to prevent/promote cell adhesion and guide cell behaviour, including inflammatory cells.
The MiNT Group bioengineers microenvironments to promote tissue repair/regeneration through modulation of the host response. Pivotal in this strategy is the concept that biomaterials can be engineered to drive inflammation towards either pro- or anti-inflammatory microenvironments. This rational has been consistently adopted by the group, with a particular emphasis in spine diseases, namely those affecting bone and the intervertebral disc.
This translational oriented research is founded on more fundamental and well-established contributions of the group to the understanding and modulation of cell-biomaterial interactions, namely on how biomaterials chemistry can be designed to prevent/promote cell adhesion and guide cell behaviour, including inflammatory cells.
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Aging cellno. 8 (2023): e13873-e13873
NPJ Regenerative medicineno. 1 (2023): 34-12
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Carla Cunha, Claudia Ribeiro Machado,Susana G. Santos, Ines A. Amaral, Catarina Correia,Joana Caldeira,Paulo Pereira,Mario A. Barbosa
TISSUE ENGINEERING PART Ano. 13-14 (2023)
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European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Societyno. 6 (2023): 1985-1991
Frontiers in bioengineering and biotechnology (2023): 1155596-1155596
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M. Bessa-Goncalves,C. Ribeiro-Machado, M. Costa, C. C. Ribeiro,J. N. Barbosa,M. A. Barbosa, S. G. Santos
TISSUE ENGINEERING PART Ano. 13-14 (2023)
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