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Michael Stratton is a cancer geneticist leading research to understand the DNA changes that cause cancer in order to improve its prevention, diagnosis and treatment. His most famous discovery was identification of the BRCA2 breast cancer gene, which is now used in predictive tests in women with a family history of the disease.
Most cancer-causing genetic mutations arise spontaneously in human cells during our lives, while some people also have cancer-driving mutations in their genome, inherited from one or both parents. Michael has discovered several inherited mutations and in 2000 set up the Cancer Genome Project at the Wellcome Trust Sanger Institute to comprehensively catalogue the spontaneous ‘somatic’ mutations that cause human cancer.
Through the Cancer Genome Project, important somatic mutations have been discovered for malignant melanoma, breast, lung, renal, bone and other cancers. Michael became Director of the Wellcome Trust Sanger Institute in 2010 and was knighted in 2013 for services to medical science.
研究兴趣
论文共 487 篇作者统计合作学者相似作者
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Sandra Perdomo,Behnoush Abedi-Ardekani,Ana Carolina de Carvalho,Aida Ferreiro-Iglesias,Valérie Gaborieau, Thomas Cattiaux, Hélène Renard, Priscilia Chopard,Christine Carreira, Andreea Spanu,Arash Nikmanesh,Ricardo Cortez Cardoso Penha,
Cell genomicsno. 3 (2024): 100500-100500
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biorxiv(2024)
Laura Torrens,Sarah Moody, Carol De Carvalho,Sergey Senkin, Saamin Cheema,Mariya Kazachkova,Valerie Gaborieau,Behnoush Abedi-Ardekani,Ricardo Cortez Cardoso Penha,Joshua Atkins, Priscilia Chopard,Jingwei Wang,
Cancer Researchno. 6_Supplement (2024): 6613-6613
Emily Mitchell, Mimy H. Pham, Anna Clay,Rashesh Sanghvi, Sandra Pietsch,Joanne I. Hsu,Hyunchul Jung, Aditi Vedi,Sarah Moody,Jingwei Wang, Daniel Leonganmornlert,Michael Spencer Chapman,
biorxiv(2024)
Behnoush ABEDI-ARDEKANI, Fannie Martin, Sergey Senkin,Sarah Moody, Thomas Cattiaux,Yichen Wang,Aida Ferreiro-Iglesias,Valerie Gaborieau,Sandra Perdomo,Laura Humphreys,Michael R. Stratton, Paul Brennan,
Kidney International Reportsno. 4 (2024): S347
Naturepp.1-9, (2024)
Laura Torrens,Sarah Moody,Ana Carolina de Carvalho,Mariya Kazachkova,Behnoush Abedi-Ardekani, Saamin Cheema,Sergey Senkin, Thomas Cattiaux,Ricardo Cortez Cardoso Penha,Joshua R Atkins,Valérie Gaborieau, Priscilia Chopard,
medRxiv : the preprint server for health sciences (2024)
Chris Hunter, Raffaella Smith,Daniel P. Cahill,Philip Stephens,Claire Stevens,Jon Teague,Chris Greenman,Sarah Edkins,Graham Bignell,Helen Davies, Sarah O'Meara,Adrian Parker,
crossref(2023)
crossref(2023)
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