During his career as a medical oncologist / hematologist, Dr. Modiano has developed a special interest in breast, lung, and gastrointestinal malignancies, and clinical trials.

In 2006, Governor Napolitano appointed Dr. Modiano a commissioner to the Arizona Biomedical Research Commission. He has received numerous research and community service awards, including the Surgeon General Certificate of Merit.

Dr. Modiano has published many peer-reviewed articles. He has also been a presenter at multiple national and international meetings.