Dr. Larché is an accomplished researcher with interests in translational medicine; the development of peptide-based vaccines for chronic immunological diseases including asthma, allergy, autoimmunity and transplantation-related diseases; the immunological mechanisms of asthma; human in vivo experimental models of T lymphocyte activation and mast cell-independent asthma; and experimental in vivo modeling of asthma, scleroderma, systemic lupus erythematosus (SLE) and GVHD.