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Dr Polak’s research interest is focused on the mechanisms of regulation of immune responses by human tissue resident dendritic cells (DCs). To be able to investigate the biology of human cutaneous DCs, she has optimized the methods for isolation of viable and functional DC subsets from different human skin compartments. Employing a variety of approaches, including in vitro analysis of DC and T cell phenotype and function, transcriptome network reconstruction and in silico modelling Dr Polak investigates the individual roles of these cell types in regulation of human cutaneous immune responses and molecular mechanisms underpinning their function
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Anna Appios,James Davies,Sofia Sirvent,Stephen Henderson,Sébastien Trzebanski,Johannes Schroth, Morven L. Law, Inês Boal Carvalho, Howard Yuan-Hao Kan, Shreya Lovlekar, Christina Major,Andres Vallejo,
biorxiv(2024)
Nature Communicationsno. 1 (2023): 1-14
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Heather C West,James Davies,Stephen Henderson, Oluyori K Adegun,Sophie Ward,Ivana R Ferrer,Chanidapa A Tye,Andres F Vallejo,Laura Jardine,Matthew Collin,Marta E Polak,Clare L Bennett
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