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个人简介
My research has been focused on understanding mutational processes in human cancer through the use of mutational signatures. In 2013, I developed the first comprehensive map of the signatures of the mutational processes that cause somatic mutations in human cancer. This work was published in several well-regarded scientific journals and highlighted by the American Society of Clinical Oncology as a milestone in the fight against cancer. More recently, I mapped the signatures of the clock-like mutational processes operative in normal somatic cells, demonstrated that mutational signatures have the potential to be used for targeted cancer therapy, and identified the mutational signatures associated with tobacco smoking. My interests, expertise, and interpersonal skills are backed up by more than 100 scientific publications, prestigious national and international awards, as well as work experience in government laboratories, renowned universities, and leading consulting companies.
研究兴趣
论文共 334 篇作者统计合作学者相似作者
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Cancer Researchno. 6_Supplement (2024): 2264-2264
Glenn J. Hanna,Alessandro Villa, Shuvro P. Nandi,Ruichao Shi,Anne Oneill,Mofei Liu,Charles T. Quinn, Nathaniel S. Treister,Herve Y. Sroussi,Piamkamon Vacharotayangul,Laura A. Goguen, Donald J. Annino Jr,
Tongwu Zhang,Jian Sang,Phuc H Hoang,Wei Zhao,Jennifer Rosenbaum, Kofi Ennu Johnson,Leszek J Klimczak, John McElderry,Alyssa Klein,Christopher Wirth,Erik N Bergstrom, Marcos Díaz-Gay,
bioRxiv : the preprint server for biology (2024)
Sandra Perdomo,Behnoush Abedi-Ardekani,Ana Carolina de Carvalho,Aida Ferreiro-Iglesias,Valérie Gaborieau, Thomas Cattiaux, Hélène Renard, Priscilia Chopard,Christine Carreira, Andreea Spanu,Arash Nikmanesh,Ricardo Cortez Cardoso Penha,
Cell genomicsno. 3 (2024): 100500-100500
Marcos Diaz-Gay,Tongwu Zhang,Azhar Khandekar,Burçak Otlu, Shuvro Nandi, Christopher D. Steele,Nathaniel Rothman, Stephen J. Chanock,Qing Lan,Ludmil B. Alexandrov,Maria Teresa Landi
Cancer Researchno. 7_Supplement (2024)
Cancer Researchno. 7_Supplement (2024)
biorxiv(2024)
bioRxiv : the preprint server for biology (2024)
Cancer Researchno. 6_Supplement (2024): 1485-1485
Cancer Researchno. 7_Supplement (2024)
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