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个人简介
Professor Chris Lord is Deputy Head of Division, Team Leader of the CRUK Gene Function Laboratory and Professor of Cancer Genomics in the Breast Cancer Now Toby Robins Research Centre at The Institute of Cancer Research, London. Much of his work focuses on exploiting genetic concepts such as synthetic lethality to identify new approaches to treating cancer and to understand the variable effectiveness of existing treatments.
More recently, Chris has focused on using high-throughput genetic perturbation screens to understand the principles that govern the robustness of synthetic lethal interactions (e.g. Elife 2020). The impact of the work led by Lord is demonstrated by the multiple biomarkers of drug sensitivity/resistance and novel synthetic lethal approaches to the treatment of ARID1A, Rb or E-cadherin defective cancers now being assessed in clinical trials.
研究兴趣
论文共 588 篇作者统计合作学者相似作者
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BRITISH JOURNAL OF CANCERpp.1-13, (2024)
E Harvey-Jones, M Raghunandan, L Robbez-Masson, L Magraner-Pardo, T Alaguthurai, A Yablonovitch, J Yen, H Xiao, R Brough, J Frankum, F Song, J Yeung,
Annals of oncology : official journal of the European Society for Medical Oncologyno. 4 (2024): 364-380
MOLECULAR ONCOLOGYno. 2 (2024): 369-385
Maria Teresa Herrera Abreu, Uzma Khalid,Jian Ning,Rosalind Cutts, Gemma Wilson,Christopher Lord,Amanda Swain,Nicholas Turner
Cancer Researchno. 9_Supplement (2024): PS12-04
Elizabeth Harvey-Jones, Maya Raghunandan, Luisa Robbez-Masson,Thanussuyah Alaguthurai,Alba Llop-Guevara, Jennifer Trendell,Olga Rodriguez,Marta Guzman,Daniel Weekes, Christelle deRenty,Eleanor Knight,Rebecca Marlow,
Cancer Researchno. 9_Supplement (2024): RF01-05
bioRxiv : the preprint server for biology (2024)
Shan Gao,Ilirjana Bajrami,Clare Verrill, Asha Kigozi,Djamila Ouaret,Tamara Aleksic,Ruth Asher,Cheng Han,Paul Allen, Deborah Bailey, Stephan Feller, Takeshi Kashima,
crossref(2023)
Ilirjana Bajrami,Jessica R. Frankum,Asha Konde,Rowan E. Miller, Farah L. Rehman,Rachel Brough,James Campbell,David Sims,Rumana Rafiq, Sean Hooper,Lina Chen,Iwanka Kozarewa,
crossref(2023)
Ilirjana Bajrami,Jessica R. Frankum,Asha Konde,Rowan E. Miller, Farah L. Rehman,Rachel Brough,James Campbell,David Sims,Rumana Rafiq, Sean Hooper,Lina Chen,Iwanka Kozarewa,
crossref(2023)
crossref(2023)
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