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职业迁徙
个人简介
My research focuses on mechanisms by which tobacco smoke chemicals initiate cancer. Organic, biological and analytical chemical methods are employed to study this problem. One of my research interests is exploring the mechanisms by which nitrosamines exert their tissue-specific carcinogenic effects. These studies indicate that DNA repair plays a critical role in the overall activity of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) as a lung specific carcinogen. Another topic of interest to me is how individuals differ in their ability to repair DNA damage caused by NNK and other tobacco carcinogens. In addition, I am investigating how other tobacco smoke chemicals influence the carcinogenic properties of NNK and other tobacco carcinogens in established rodent tumor models.
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CARCINOGENESIS (2024)
Chemical research in toxicologyno. 2 (2023): 157-161
Susan Marie Viet,Jill C. Falman, Lori S. Merrill,Elaine M. Faustman,David A. Savitz,Nancy Mervish,Dana B. Barr,Lisa A. Peterson,Robert Wright,David Balshaw, Barbara O'Brien
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