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RESEARCH INTERESTS
Our laboratory is interested in developing innovative approaches to regenerate or repair an injured heart. Our goal is to understand the molecular basis of cardiomyocyte specification and maturation and apply this knowledge to improve efficiency and clinical applicability of cellular reprogramming in heart disease. To achieve these goals, we utilize in vivo modeling of cardiac disease in the mouse, including myocardial infarction (MI), cardiac hypertrophy, chronic heart failure and congenital heart disease (CHD). In addition, we take advantage of traditional mouse genetics, cell and molecular biology, biochemistry and newly developed reprogramming technologies (iPSC and iCM) to investigate the fundamental events underlying the progression of various cardiovascular diseases as well as to discover the basic mechanisms of cell reprogramming.
研究兴趣
论文共 174 篇作者统计合作学者相似作者
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Paige Takasugi,Li Qian
Juntao Fang,Qiangbing Yang,Renée G. C. Maas,Michele Buono, Bram Meijlink, Dyonne Lotgerink Bruinenberg,Ernest Diez Benavente,Michal Mokry,Alain van Mil,Li Qian,Marie-José Goumans,Raymond Schiffelers,
Stem Cell Research & Therapyno. 1 (2024): 1-16
Yanhan Dong,Yuchen Yang,Haofei Wang, Dong Feng, Elizabeth Nist, Nicholas Yapundich,Brian Spurlock, Madison Craft,Li Qian,Jiandong Liu
Science advancesno. 8 (2024): eadk4694-eadk4694
Tiffany A Garbutt, Zhenhua Wang,Haofei Wang,Hong Ma,Hongmei Ruan,Yanhan Dong,Yifang Xie, Lianmei Tan, Ranan Phookan, Joy Stouffer,Vasanth Vedantham,Yuchen Yang,
Circulation (2024)
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINEno. 2 (2023)
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CIRCULATION RESEARCH (2023)
Cellular reprogrammingno. 3 (2023): 83-87
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JACC-BASIC TO TRANSLATIONAL SCIENCEno. 1 (2023): 145-160
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