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个人简介
Dr. Leonidas “Leo” Stamatatos and his team of researchers explore how antibody-producing B cells respond to infection and vaccination. Using diverse experimental approaches, the researchers also design and test ways to stimulate B cells into producing the antibodies deemed most likely to succeed against a chosen virus. Much of the work focuses on getting B cells to make antibodies that can provide sustained protection against HIV, which is adept at evading conventional vaccines through rapid genetic mutation. The group’s work encompasses the many stages in the development of candidate vaccines. These range from early, basic research on the structure of antibodies and their targets to detailed evaluation of the level of protection they provide to human volunteers in clinical trials.
研究兴趣
论文共 253 篇作者统计合作学者相似作者
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Manon Termote, Rafael C. Marques, Erik Hyllner, Mariia V. Guryleva, Mirthe Henskens, Andreas Brutscher, Isabel J.L. Baken,Xaquin Castro Dopico, Adria Dalmau Gasull, Benjamin Murrell,Leonidas Stamatatos,Lisa S. Westerberg,
biorxiv(2024)
Current opinion in HIV and AIDSno. 6 (2023): 309-314
biorxiv(2023)
Shridhar Bale,Lifei Yang, Mehrdad Alirezaei,Richard Wilson,Takayuki Ota, Esmeralda D Doyle,Christopher A Cottrell,Javier Guenaga,Karen Tran,Wenjuan Li,Leonidas Stamatatos,David Nemazee,
Frontiers in immunology (2023): 1180959-1180959
biorxiv(2022)
Science Advancesno. 18 (2022)
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