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His research group has made important contributions to establish that estrogen receptor-positive and-negative breast cancers have fundamentally different molecular, clinical and epidemiological characteristics. He has been a pioneer in evaluating gene expression profiling as a diagnostic technology to predict chemotherapy and endocrine therapy sensitivity and have shown that different biological processes are involved in determining the prognosis and treatment response in different breast cancer subtypes. His group has also developed new bioinformatics tools to integrate information from across different data platforms in order to define the molecular pathways that are disturbed in individual cancers and could provide the bases for individualized treatment strategies. He made important contributions to clarify the clinical value of preoperative (neoadjuvant) chemotherapy in different breast cancer subtypes. Dr Pusztai is also principal investigator of several clinical trials investigating new drugs, including immunotherapies for breast cancer. He has published over 250 scientific manuscripts in high impact medical journals including the NEJM, JAMA, Journal of Clinical Oncology, Nature Biotechnology, PNAS, Lancet Oncology and JNCI. He is among the top 1% most highly cited clinical investigators in medicine over the past 10 years according to a 2015 Thomson Reuters report. He is Associate Editor of the Journal of National Cancer Institute (JNCI), member of the Scientific Advisory Board of the Breast Cancer Research Foundation, former member of the NCI North American Breast Cancer Steering Committee and Co-Chair of the Trans-ALTTO Committee and Chair of the Data Safety Monitoring Committee of the OPTIMA trial in the United Kingdom.
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论文共 1167 篇作者统计合作学者相似作者
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Cancer Researchno. 6_Supplement (2024): 1207-1207
Alejandro Ríos-Hoyo,Erin Cobain,Laura A Huppert, Peter D Beitsch,Thomas A Buchholz,Laura Esserman, Laura J van 't Veer,Hope S Rugo,Lajos Pusztai
Kathy S. Albain,Christina Yau,Emanuel F. Petricoin,Denise M. Wolf, Julie E. Lang,A. Jo Chien, Tufia Haddad,Andres Forero-Torres,Anne M. Wallace,Henry Kaplan,Lajos Pusztai, David Euhus,
CLINICAL CANCER RESEARCHno. 4 (2024): 729-740
CANCER RESEARCHno. 3 (2024)
Magdalena M. Coman,Lajos Pusztai,Regina Hooley, Liva Andreveja,Leah Kim,Nikhil Joshi,Alexey Bersenev,Diane Krause,Tristen S. Park
JOURNAL OF IMMUNOTHERAPYno. 2 (2024): 49-53
Giampaolo Bianchini,Takayuki Iwamoto,Yuan Qi,Charles Coutant, Christine Y. Shiang, Bailang Wang,Libero Santarpia,Vicente Valero,Gabriel N. Hortobagyi,W. Fraser Symmans,Luca Gianni,Lajos Pusztai
crossref(2023)
S. Loi,G. Curigliano,R.F. Salgado, R.I. Romero Diaz,S. Delaloge, C. Rojas,M. Kok,C. Saura Manich, N. Harbeck, E.A. Mittendorf,D. Yardley,L. Pusztai,
Annals of Oncology (2023): S1259-S1260
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