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职业迁徙
个人简介
The main research focus of my research group is identifying the role of glia in neurodegenerative conditions, with particular interest in Motor Neurone Disease (MND). Our primary aim is to develop therapeutic strategies using gene therapy approaches.
In MND, like in many other neurodegenerative disorders, neuronal damage and death are the most striking signs of disease, however, our research, along with the work of others, has demonstrated that glia play an active role in neuronal degeneration.
We use various in vitro cell models, including primary cells and genetically reprogrammed human progenitor cells, to investigate the interaction between astrocytes and oligodendrocytes from patients affected by MND with neurons.
研究兴趣
论文共 99 篇作者统计合作学者相似作者
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Calum Harvey, Marcel Weinreich, James A. K. Lee,Allan C. Shaw,Laura Ferraiuolo,Heather Mortiboys,Sai Zhang,Paul J. Hop,Ramona A. J. Zwamborn,Kristel van Eijk,Thomas H. Julian,Tobias Moll,
HELIYONno. 3 (2024): e24975-e24975
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medRxiv : the preprint server for health sciences (2024)
crossref(2024)
Ana Aragón-González,Allan C Shaw, Jannigje R Kok,Florence S Roussel,Cleide dos Santos Souza, Sarah M Granger,Tatyana Vetter, Yolanda de Diego,Kathrin C Meyer, Selina N Beal,Pamela J Shaw,Laura Ferraiuolo
Fluids and Barriers of the CNSno. 1 (2024): 1-14
Frontiers in Molecular Medicine (2024)
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Wing Hei Au,Leonor Miller-Fleming,Alvaro Sanchez-Martinez, James Lee,Madeleine J Twyning,Hiran Prag, Sarah Granger, Katie Roome,Laura Ferraiuolo,Heather Mortiboys,Alexander J Whitworth
biorxiv(2023)
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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