基本信息
浏览量:60
职业迁徙
个人简介
Research Interests
Functional genomics with an emphasis on optimizing intestinal function to promote animal health and productivity. Our laboratory is focused on using comparative genomics to study animal health and development across species. Ongoing studies include a functional nutritional genomics project in collaboration with Professor George Fahey. This model is exploring the changes in gene expression during growth in young dogs compared to aged animals on different diets. These studies are designed to identify pathways that lead to wellness in aged animals and how through nutritional intervention diseases of aged animals can be avoided or ameliorated. Our efforts also address the interaction of animal health and nutrition. We are establishing in vitro gastrointestinal epithelial systems as technology platforms to study changes in gene expression during responses to pathogens. Finally, another major focus in our program is to develop animal models based on functional genomics to study mucosal development. In collaboration with Professor Rex Gaskins, of the Department of Animal Sciences, we are developing artificial intestinal crypts using microtechnolgy and laser capture micrscopy to explore gene expression of individual cells as they differentiate from the crypt stem cells. This will allow us to identify regulatory signals from nutritional sources and endogenous microbiota promoting epithelial differentiation.
研究兴趣
论文共 309 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Mammalian genome : official journal of the International Mammalian Genome Societyno. 4 (2023): 520-530
Cancer Researchno. 12 (2022): 785-785
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn