基本信息
浏览量:142
职业迁徙
个人简介
Research areas and keywords
Cancer and Oncology
Tumor microenvironment , Targeted therapy, Mouse models of cancer
Research
We aim to molecularly map the support functions performed by the various cell types comprising the tumor microenvironment. We believe that decisive treatment benefit can only be achieved by targeting distinct cell types and pathways that collectively sustain tumor
growth.
Specifically, molecular interactions between cancer-associated fibroblasts, pericytes and endothelial cells are explored with a special focus on novel anti-cancer strategies. Importantly, the cellular networks within tumors cannot be studied in isolation. Thus, our work ranges over many different topics, with methodology, technology and purpose as the common denominators.
We currently pursue three main avenues of research:
1. Basic Biology
Identification of new cellular subsets of the tumor stroma and their influence on
cancer progression
2. Pre-clinical studies Investigation of the therapeutic utility of the tumor stroma
3. Translational studies
Exploration of the tumor stroma as biomarkers of prognosis or response to
therapy in human cancer
Taken together, the overall aim of our work is to generate basic knowledge about the interdependent way cells within a tumor relate to each other, as well as produce information that will be immediately useful for the design and modification of clinical practice.
Cancer and Oncology
Tumor microenvironment , Targeted therapy, Mouse models of cancer
Research
We aim to molecularly map the support functions performed by the various cell types comprising the tumor microenvironment. We believe that decisive treatment benefit can only be achieved by targeting distinct cell types and pathways that collectively sustain tumor
growth.
Specifically, molecular interactions between cancer-associated fibroblasts, pericytes and endothelial cells are explored with a special focus on novel anti-cancer strategies. Importantly, the cellular networks within tumors cannot be studied in isolation. Thus, our work ranges over many different topics, with methodology, technology and purpose as the common denominators.
We currently pursue three main avenues of research:
1. Basic Biology
Identification of new cellular subsets of the tumor stroma and their influence on
cancer progression
2. Pre-clinical studies Investigation of the therapeutic utility of the tumor stroma
3. Translational studies
Exploration of the tumor stroma as biomarkers of prognosis or response to
therapy in human cancer
Taken together, the overall aim of our work is to generate basic knowledge about the interdependent way cells within a tumor relate to each other, as well as produce information that will be immediately useful for the design and modification of clinical practice.
研究兴趣
论文共 185 篇作者统计合作学者相似作者
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时间
引用量
主题
期刊级别
合作者
合作机构
biorxiv(2024)
Linglong Huang, Mercedes Herrera,Jonas Sjölund, Vladimir Chocoloff,Simon Joost, Rasul M. Tabiev, Lina Wik Leiss,Carina Strell,Luis Nunes,Artur Mezheyeuski, David Edler,Anna Martling,
Cancer Researchno. 6_Supplement (2024): 6970-6970
Upsala journal of medical sciences (2024): 1-5
Mikkel Morsing Bagger,Jonas Sjölund,Jiyoung Kim, Katharina Theresa Kohler,René Villadsen,Abbas Jafari,Moustapha Kassem,Kristian Pietras,Lone Rønnov-Jessen,Ole William Petersen
Breast Cancer Researchno. 1 (2024): 1-19
Cellular & molecular immunologyno. 1 (2024): 91-94
Steven E. Reid, Jessica Pantaleo, Paulina Bolivar,Matteo Bocci,Jonas Sjölund,Mikkel Morsing,Eugenia Cordero,Sara Larsson, Maria Malmberg,Brinton Seashore-Ludlow,Kristian Pietras
Oncogeneno. 15 (2024): 1-14
crossref(2023)
Frontiers in Immunology (2023)
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