Krishna Saxena - Goethe-Universitat Frankfurt am Main

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论文共 89 篇作者统计合作学者相似作者

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Biochemical Investigation of LC3/GABARAP-ligand Interaction As an Important Quality Measure for LC3/GABARAP-targeting Small Molecules: Addendum to the Guidelines (4th Edition)

Martin P Schwalm, Christopher Lenz,Krishna Saxena, Daniel J Klionsky,Ewgenij Proschak,Stefan Knapp

Autophagypp.1-5, (2025)

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Crystallographic Fragment Screening Reveals Ligand Hotspots in TRIM21 PRY-SPRY Domain

Yeojin Kim, Aleksandar Lučić, Christopher Lenz, Frederic Farges, Martin P Schwalm,Krishna Saxena, Thomas Hanke, Peter G Marples, Jasmin C Aschenbrenner,Daren Fearon,Frank von Delft, Andreas Krämer,Stefan Knapp

Communications chemistryno. 1 (2025): 185-185

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Differential Effects of the N-terminal Helix of FGF8b on the Activity of a Small-Molecule FGFR Inhibitor in Cell Culture and for the Extracellular Domain of FGFR3c in Solution

Konstantin S. Mineev,Bruno Hargittay, Jing Jin,Claudia Catapano,Marina S. Dietz, Marta Segarra, Mark S. Harwardt,Christian Richter,Hendrik R. A. Jonker,Krishna Saxena,Sridhar Sreeramulu,Mike Heilemann,Amparo Acker-Palmer,Harald Schwalbe

FEBS LETTERSno. 20 (2024): 2518-2532

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A C-Degron Structure-Based Approach for the Development of Ligands Targeting the E3 Ligase TRIM7

Christian J. Munoz Sosa,Christopher Lenz, Anton Hamann, Frederic Farges,Johannes Dopfer,Andreas Kraemer, Veronika Cherkashyna,Andrey Tarnovskiy,Yurii S. Moroz,Ewgenij Proschak,Vaclav Nemec,Susanne Mueller,Krishna Saxena,Stefan Knapp

ACS CHEMICAL BIOLOGYno. 7 (2024): 1638-1647

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Luciferase- and HaloTag-based Reporter Assays to Measure Small-Molecule-induced Degradation Pathway in Living Cells

Martin P. Schwalm,Krishna Saxena,Susanne Mueller,Stefan Knapp

Nature Protocolspp.1-41, (2024)

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Critical Assessment of LC3/GABARAP Ligands Used for Degrader Development and Ligandability of LC3/GABARAP Binding Pockets

NATURE COMMUNICATIONSno. 1 (2024)

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Back-Pocket Optimization of 2-Aminopyrimidine-based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors

Joshua Gerninghaus,Rezart Zhubi, Andreas Kra''mer,Marwah Karim,Do Hoang Nhu Tran,Andreas C. Joerger, Christian Schreiber,Lena M. Berger,Benedict-Tilman Berger,Theresa A. L. Ehret,Lewis Elson,Christopher Lenz,Krishna Saxena, Susanne Mu''ller,Shirit Einav,Stefan Knapp,Thomas Hanke

JOURNAL OF MEDICINAL CHEMISTRYno. 15 (2024): 12534-12552

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Targeting LC3/GABARAP for degrader development and autophagy modulation

bioRxiv (Cold Spring Harbor Laboratory) (2023)

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NMR Resonance Assignment of a Fibroblast Growth Factor 8 Splicing Isoform B

Bruno Hargittay,Konstantin S. Mineev,Christian Richter,Sridhar Sreeramulu,Hendrik R.A. Jonker,Krishna Saxena,Harald Schwalbe

Biomolecular NMR Assignmentsno. 1 (2023): 135-142

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Cover Feature: Optimization of the Lead Compound NVP‐BHG712 As a Colorectal Cancer Inhibitor (chem. Eur. J. 23/2023)

Alix Tröster,Michael DiPrima,Nathalie Jores,Denis Kudlinzki,Sridhar Sreeramulu,Santosh L. Gande,Verena Linhard,Damian Ludig, Alexander Schug,Krishna Saxena,Maria Reinecke,Stephanie Heinzlmeir,Matthias S. Leisegang,Jan Wollenhaupt,Frank Lennartz,Manfred S. Weiss,Bernhard Kuster,Giovanna Tosato,Harald Schwalbe

Chemistry – A European Journalno. 23 (2023)

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