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Klaus Schulten is a leader in the field of computational biophysics, having devoted over 40 years to establishing the physical mechanisms underlying processes and organization in living systems from the atomic to the organism scale. Schulten is a strong proponent of the use of simulations as a "computational microscope", to augment experimental research, and to lead to discoveries that could not be made through experiments so far. The molecular dynamics and structure analysis programs NAMD and VMD, born and continuously developed in his group, are used today by many thousands of researchers across the world. Schulten contributed key discoveries to several areas of biological physics: from quantum biology of vision, photosynthesis, and animal navigation to ion channels employed in neural signaling and to neural network organization of brain function; from mechanically gated channel proteins to muscle protein mechanics; from mathematical physics of non-equilibrium processes to numerical mathematics of the classical many-body problem. While Schulten's work remains solidly anchored to molecular detail, his most recent work has advanced to molecular cell biology and molecular systems biology via his group's structure analysis method, Molecular Dynamics Flexible Fitting, applied to systems such as the 300,000 atom ribosome and 4 million atom asymmetric HIV capsid. As of 2013, Schulten's work in biological physics has produced over 660 publications, which have been cited over 80,000 times (Google Scholar) as of August 2015. Schulten believes strongly in the importance of educating the next generation of scientists, having graduated 80 PhD students so far, many today in distinguished academic positions. He developed new courses and textbooks, and organizes a popular series of hands-on training workshops in which he has trained, in small groups, over 1,000 young scientists.
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