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个人简介
The research in our laboratory is focused on the molecular mechanisms of translational control in the brain, how they are involved in activity-dependent, long-lasting changes in neuronal function, and whether these mechanisms play a role in complex behaviors, including cognition. We also study how dysregulated translational control contributes to altered synaptic plasticity and aberrant behavior in mouse models of fragile X syndrome, intellectual disability, autism spectrum disorder, and Alzheimer's disease. We use a number of experimental approaches, including genetic, molecular, biochemical, optical, electrophysiology, and imaging experiments to delineate the molecular signaling cascades that couple receptors to the translational apparatus during long-lasting synaptic plasticity in the hippocampus, amygdala, cortex, and striatum, and whether these types of translational control are required for memory formation, social behaviors, and behavioral flexibility.
研究兴趣
论文共 254 篇作者统计合作学者相似作者
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Mauricio M. Oliveira,Muhaned Mohamed,Megan K. Elder, Keylin Banegas-Morales,Maggie Mamcarz, Emily H. Lu, Ela A. N. Golhan, Nishika Navrange,Snehajyoti Chatterjee,Ted Abel,Eric Klann
CELL REPORTSno. 2 (2024): 113670-113670
Cell Reportsno. 8 (2023): 112901-112901
Proceedings of the National Academy of Sciences of the United States of Americano. 30 (2023)
Vijendra Sharma,Mauricio M Oliveira, Rapita Sood,Abdessattar Khlaifia,Danning Lou,Mehdi Hooshmandi, Tzu-Yu Hung,Niaz Mahmood, Maya Reeves, David Ho-Tieng, Noah Cohen, Po-Chieh Cheng,
Proceedings of the National Academy of Sciences of the United States of Americano. 49 (2023): e2308671120-e2308671120
Jessica M Alapin,Muhaned S Mohamed,Prerana Shrestha, Houda G Khaled, Anna G Vorabyeva,Heather L Bowling,Mauricio M Oliveira,Eric Klann
bioRxiv : the preprint server for biology (2023)
The Journal of neuroscience : the official journal of the Society for Neuroscienceno. 45 (2023): 7483-7488
Frontiers in cellular neuroscience (2023): 1219270
Trends in Neurosciencesno. 4 (2022): 297-311
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