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We can see human body as a small chemical plant thorough glasses of chemical engineering. Each organ is a unit-operation device. Chemical engineering together with real collaboration between engineering and medicine is a powerful tool for creation, development and improvement of "artificial organs". Our research interest is how we can develop a "wearable artificial kidney". Its miniaturization, development of highly biocompatible materials, positive control of membrane permeability and also settlement of peculiar problems to an artificial system are essential to its realization. Hence, we grope for artificial biomaterials with excellent biocompatibility by evaluating a relationship between nano three-dimensional structure and surface biocompatibility. Using a novel transport model replacing the conventional time-consuming try & error method, we also aim for highly permeable membrane design. Native membrane pore structures in water are observed by atomic force microscopy (AFM). Membranes with any control ability of diffusive permeability in proportion to solute concentration are prepared by the molecular imprinting technique. Membranes with excellent blocking efficiency for endotoxin and toxic substances in dialysate are also prepared by a nanoscopic technique. Furthermore, functional membranes capable of removing active oxygen species are prepared using a novel sensing technique that positively produces a new evaluation method and concomitantly quite functional biomaterials.
We can see human body as a small chemical plant thorough glasses of chemical engineering. Each organ is a unit-operation device. Chemical engineering together with real collaboration between engineering and medicine is a powerful tool for creation, development and improvement of "artificial organs". Our research interest is how we can develop a "wearable artificial kidney". Its miniaturization, development of highly biocompatible materials, positive control of membrane permeability and also settlement of peculiar problems to an artificial system are essential to its realization. Hence, we grope for artificial biomaterials with excellent biocompatibility by evaluating a relationship between nano three-dimensional structure and surface biocompatibility. Using a novel transport model replacing the conventional time-consuming try & error method, we also aim for highly permeable membrane design. Native membrane pore structures in water are observed by atomic force microscopy (AFM). Membranes with any control ability of diffusive permeability in proportion to solute concentration are prepared by the molecular imprinting technique. Membranes with excellent blocking efficiency for endotoxin and toxic substances in dialysate are also prepared by a nanoscopic technique. Furthermore, functional membranes capable of removing active oxygen species are prepared using a novel sensing technique that positively produces a new evaluation method and concomitantly quite functional biomaterials.
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论文共 190 篇作者统计合作学者相似作者
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Journal of Artificial Organsno. 2 (2024): 1-8
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