His research is in image processing and medical imaging. Parker is an inventor/pioneer in a number of enterprises, including the field of sonoelastography and the international conference series in that area, and the Blue Noise Mask. He is the recipient of the Eastman Medal, the AIUM Joseph Holmes Pioneer Award for Contributions to Medical Ultrasound, the Eastman Kodak Outstanding Innovation Award, and the Ultrasound in Medicine and Biology World Federation Prize. He holds 28 U.S. patents and 14 international patents that have been licensed to 25 companies. He is a founder of VirtualScopics, Inc. Parker has published 270+ journal articles and numerous book chapters. He is a fellow of the Institute of Electrical & Electronics Engineers (IEEE), the American Institute of Ultrasound in Medicine (AIUM), the Acoustical Society of America (ASA), the American Institute for Medical and Biological Engineering (AIMBE), and the National Academy of Inventors (NAI).