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职业迁徙
个人简介
My background and research are in translational immunology. I am interested in understanding the basis for autoimmune diseases and developing new therapies based on our understanding of disease mechanisms. My focus has largely been in the field of autoimmune Type 1 diabetes. The work encompasses basic laboratory work as well as clinical studies to understanding the regulation of autoreactive T cells to clinical trials that involve novel therapeutics. As part of these studies I have also been very interested in analysis of beta cell function in Type 1 diabetes. As part of this interest, we have been studying the development of autoimmune diabetes in patients with cancers who are treated with checkpoint inhibitors. Our clinical and basic studies are focused on understanding how beta cells are destroyed and react to inflammation. Finally, with the COVID-19 pandemic, we have been studying the immunologic basis for responses in children and adults who are hospitalized with COVID-19 to understand the mechanisms that can lead to disease protection.
研究兴趣
论文共 282 篇作者统计合作学者相似作者
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Esther Latres,Carla J Greenbaum, Maria L Oyaski,Colin M Dayan,Helen M Colhoun,John M Lachin,Jay S Skyler,Michael R Rickels,Simi T Ahmed, Sanjoy Dutta,Kevan C Herold, Marjana Marinac
Diabetes (2024)
TRANSPLANT INTERNATIONAL (2024): 12320-12320
The Journal of clinical endocrinology and metabolism (2024)
Nature Reviews Immunologypp.1-17, (2024)
Carl A. Pierce, Lip Nam Loh,Holly R. Steach, Natalia Cheshenko,Paula Preston-Hurlburt,Fengrui Zhang, Stephanie Stransky, Leah Kravets, Simone Sidoli,William Philbrick, Michel Nassar, Smita Krishnaswamy,
JOURNAL OF CLINICAL INVESTIGATIONno. 11 (2023)
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