Kenneth M Pfarr

My lab is working to understand the molecular basis of the symbiosis between filarial nematodes and Wolbachia endobacteria. The intracellular bacteria are essential for worm development and survival and have become a useful target in controlling filarial diseases. By understanding the exact nature of the symbiosis, we hope to develop better, more effective drug therapies targeting the Wolbachia for use in endemic countries.