Kazuhiro Iwai

CREST, Japan Science and Technology Corporation (JST), Kawaguchi 332-0012, Japan

Show Academic Trajectory

Ego Network

D-Core

Research Interests

Author Statistics

Experience

Education

Bio

None

Papers185 papers

Sort

By YearBy Citation

The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC

Yasuhiro Fuseya,Hiroaki Fujita,Minsoo Kim,Fumiaki Ohtake, Akira Nishide, Katsuhiro Sasaki,Yasushi Saeki,Keiji Tanaka,Ryosuke Takahashi,Kazuhiro Iwai

Nature cell biology, no. 6 (2020): 663-673

WOSBibtex

Linear ubiquitin assembly complex regulates lung epithelial driven responses during influenza infection

Patricia L Brazee,Luisa Morales-Nebreda, Natalia D Magnani, Joe Gn Garcia,Alexander V Misharin,Karen M Ridge,G R Scott Budinger,Kazuhiro Iwai,Laura A Dada,Jacob I Sznajder

JOURNAL OF CLINICAL INVESTIGATION, no. 3 (2020): 1301.0-1314.0

WOSBibtex

Discovery of linear ubiquitination, a crucial regulator for immune signaling and cell death

Kazuhiro Iwai

FEBS Journal, (2020)

Bibtex

LUBAC accelerates B-cell lymphomagenesis by conferring B cells resistance to genotoxic stress

Tomoyasu Jo, Momoko Nishikori, Yasunori Kogure, Hiroshi Arima, Katsuhiro Sasaki, Yoshiteru Sasaki, Tomoko Nakagawa,Fumie Iwai,Shuji Momose, Aki Shiraishi,Hiroshi Kiyonari, Noritaka Kagaya

Blood, (2020)

WOSBibtex

Specific heme binding to heme regulatory motifs in iron regulatory proteins and its functional significance

Yudai Nishitani, Hirotaka Okutani, Yukiko Takeda, Takeshi Uchida,Kazuhiro Iwai,Koichiro Ishimori

Journal of Inorganic Biochemistry, (2019): 110726

WOSBibtex

LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochores

Min Wu,Yan Chang, Huaibin Hu,Rui Mu,Yucheng Zhang,Xuanhe Qin, Xiaotao Duan,Weihua Li,Haiqing Tu,Weina Zhang, Guang Wang, Qiuying Han

Nature communications, no. 1 (2019): 273

WOSBibtex

Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death

Katsuhiro Sasaki, Ai Himeno, Tomoko Nakagawa, Yoshiteru Sasaki,Hiroshi Kiyonari,Kazuhiro Iwai

Nature communications, no. 1 (2019): 3878-16

WOSBibtex

LUBAC-mediated immune regulation for tissue homeostasis

Katsuhiro Sasaki,Kazuhiro Iwai

The Molecular Biology Society of Japan, (2019)

Bibtex

NMR resonance assignments of the NZF domain of mouse HOIL-1L free and bound to linear di-ubiquitin

Naoki Ishii,Erik Walinda, Naoto Iwakawa,Daichi Morimoto,Kazuhiro Iwai,Kenji Sugase,Masahiro Shirakawa

Biomolecular NMR assignments, no. 1 (2018): 149-153

WOSBibtex

Regulation of cellular iron metabolism: Iron-dependent degradation of IRP by SCF FBXL5 ubiquitin ligase

Kazuhiro Iwai

Free Radical Biology and Medicine, (2018): 64-68

WOSBibtex

NMR resonance assignments of the NZF domain of mouse HOIL-1L in free form and linear di-ubiquitin-bound form

Naoki Ishii,Erik Walinda, Naoto Iwakawa,Daichi Morimoto,Kazuhiro Iwai,Kenji Sugase,Masahiro Shirakawa

Journal of Back and Musculoskeletal Rehabilitation, (2018)

Bibtex

Redox-dependent axial ligand replacement and its functional significance in heme-bound iron regulatory proteins

Mariko Ogura, Ryosuke Endo,Haruto Ishikawa,Yukiko Takeda,Takeshi Uchida,Kazuhiro Iwai,Kazuo Kobayashi,Koichiro Ishimori

Journal of Inorganic Biochemistry, (2018): 238-248

Cited by1WOSBibtex

Crucial Role of Linear Ubiquitin Chain Assembly Complex-Mediated Inhibition of Programmed Cell Death in TLR4-Mediated B Cell Responses and B1b Cell Development

Yoshiteru Sasaki,Kazuhiro Iwai

Journal of immunology (Baltimore, Md. : 1950), (2018)

WOSBibtex

SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth

Hironari Tamiya,Hyungsoo Kim, Oleksiy Klymenko,Heejung Kim,Yongmei Feng,Tongwu Zhang, Ji Yun Han, Ayako Murao, Scott J Snipas,Lucia Jilaveanu,Kevin Brown,Harriet Kluger

JOURNAL OF CLINICAL INVESTIGATION, no. 1 (2018): 517-530

Cited by4WOSBibtex

Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization

Hiroaki Fujita,Akira Tokunaga,Satoshi Shimizu, Amanda L Whiting, Francisco Aguilar-Alonso,Kenji Takagi,Erik Walinda,Yoshiteru Sasaki, Taketo Shimokawa,Tsunehiro Mizushima,Izuru Ohki,Mariko Ariyoshi

Cell Reports, no. 4 (2018): 1192-1204

Cited by8WOSBibtex

HOIL1 is essential for the induction of type I and III interferons by MDA5 and regulates persistent murine norovirus infection

Donna A MacDuff,Megan T Baldridge, Arwa M Qaqish,Timothy J Nice, Azad D Darbandi, Victoria L Hartley, Stefan T Peterson,Jonathan J Miner,Kazuhiro Iwai,Herbert W Virgin

Journal of virology, (2018)

WOSBibtex

HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains

Yuri Shibata,Fuminori Tokunaga,Eiji Goto, Ginga Komatsu,Jin Gohda,Yasushi Saeki,Keiji Tanaka,Hirotaka Takahashi,Tatsuya Sawasaki, Satoshi Inoue,Hiroyuki Oshiumi,Tsukasa Seya

PLOS Pathogens, no. 1 (2017)

Cited by5Bibtex

Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy

Yukiko Yoshida, Sayaka Yasuda, Toshiharu Fujita,Maho Hamasaki,Arisa Murakami,Junko Kawawaki,Kazuhiro Iwai,Yasushi Saeki,Tamotsu Yoshimori,Noriyuki Matsuda,Keiji Tanaka

Proceedings of the National Academy of Sciences of the United States of America, no. 32 (2017): 8574-8579

Cited by9WOSBibtex

Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy

Seiji Kaji,Takakuni Maki, Hisanori Kinoshita,Norihito Uemura,Takashi Ayaki,Yasuhiro Kawamoto,Takahiro Furuta,Makoto Urushitani,Masato Hasegawa, Yusuke Kinoshita, Yuichi Ono, Xiaobo Mao

Stem cell reports, (2017)

Cited by1WOSBibtex

Ubiquitination of exposed glycoproteins by SCF(FBXO27) directs damaged lysosomes for autophagy

Yukiko Yoshida, Sayaka Yasuda, Toshiharu Fujita, Maho Hamasaki, Arisa Murakami, Junko Kawawaki,Kazuhiro Iwai, Yasushi Saeki, Tamotsu Yoshimori,Noriyuki Matsuda, Keiji Tanaka

Proceedings of the National Academy of Sciences of the United States of America, (2017)

WOSBibtex

View All

Base Info Papers Patents Projects