Her research interests are the maintenance of health in later life and the causes and prevention of chronic disease including cancer and cardiovascular disease with a focus on nutrition and hormones. Her research involves large population studies and clinical trials. She was a founding principal investigator in the European Prospective Investigation into Cancer in Norfolk, part of a 10 country half a million participant research collaboration ongoing over three decades. She has coordinated since 1989 an International Society of Cardiovascular Disease Epidemiology and Prevention annual Ten Day Training seminar training over 1600 physicians and scientists from over 100 countries and has supervised over 25 PhD candidates.