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个人简介
The research interests of the Whitehead Lab lie at the interface of chemical engineering, molecular biology, and medicine. The group’s ultimate goal is to engineer safe and effective drug delivery systems capable of achieving therapeutic outcomes in biological models and, ultimately, in humans. As a first step, the Whitehead Lab is interested in developing a fundamental understanding of the relationship between delivery barrier biology and drug transport. To accomplish this, the group is employing RNA interference, a biological phenomenon that induces gene silencing in the presence of siRNA. Through the identification of cellular components essential to the drug transport process, the group is able to design delivery systems using modern chemical techniques to overcome or cooperate with those components. Specifically, Whitehead’s Lab is interested in the development of delivery systems for the nucleus, the intestinal epithelium, and various leukocytes, including B lymphoma cells.
研究兴趣
论文共 153 篇作者统计合作学者相似作者
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Harrison Lawson, Huy Nguyen, Ayesha Tupe,Mariah Arral, Keng Lee,Mengrou Lu,Kathryn Whitehead,Si-Yang Zheng
crossref(2024)
Serena Omo-Lamai, Yufei Wang, Manthan N Patel,Eno-Obong Essien,Mengwen Shen, Aparajeeta Majumdar, Carolann Espy,Jichuan Wu,Breana Channer, Michael Tobin,Shruthi Murali,Tyler E Papp,
bioRxiv : the preprint server for biology (2024)
PLOS ONEno. 1 (2024): e0297821-e0297821
Namit Chaudhary,Alexandra N Newby, Mariah L Arral,Saigopalakrishna S Yerneni,Samuel T LoPresti,Rose Doerfler, Daria M Strelkova Petersen, Catalina Montoya, Julie S Kim, Bethany Fox,Tiffany Coon, Angela Malaney,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V (2023): 126-135
Journal of controlled release : official journal of the Controlled Release Society (2023): 389-401
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biorxiv(2023)
ASAIO journal (American Society for Artificial Internal Organs : 1992)no. 6 (2023): 527-532
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