Kathryn L. Lunetta, Ph.D. is a Professor of Biostatistics and a statistical geneticist with more than 20 years of experience in statistics and genetics research. She has extensive experience with the design and analysis of genome- wide association studies and sequencing studies and collaborate on several large, national and international genetic epidemiology studies at Boston University and with the Framingham Heart study. Her methodological research focuses on statistical problems and study design and analysis issues in human genetics, particularly in the mapping of complex genetic diseases. Her collaborative work spans several fields, including the genetics of atrial fibrillation and related phenotypes, the genetics of healthy aging and reproduction, and Alzheimer disease. She is a member of the CHARGE (Cohorts for Heart and Aging Research) consortium and participates on the Steering and Analysis committees, and also a TOPMed investigator and analysis committee member. She is senior/primary statistician on several Alzheimer Disease related projects and for the Framingham Heart Study Atrial Fibrillation working groups, where she advises on methodology and long-term goals and provide day- to-day supervision of analyses. She is multi-PI of a Framingham Immune cell and brain aging project that seeks to identify immune cell and inflammatory biomarkers related to cognitive aging.