基本信息
浏览量:104
职业迁徙
个人简介
I am a Pediatric Hematologist-Oncologist at Dana-Farber / Boston Children’s Cancer and Blood Disorders Center with clinical and research expertise in precision cancer medicine and solid tumors, particularly sarcomas. The focus of my research is the genomics of pediatric solid tumors including expanding the benefits of the precision cancer medicine approach to children with these cancers and a poor prognosis. In addition, I perform clinical trials of new therapies for pediatric sarcomas. My prior work has defined the genomic underpinnings of osteosarcoma and gastrointestinal stromal tumor, determined that non-standard personalized medicine tests are commonly marketed to cancer patients as being beneficial, established that a multi-institutional precision medicine study is feasible and demonstrated that a significant proportion of children with difficult to treat childhood solid tumors have genomic results with potential clinical benefit. I am the lead pediatric investigator for a comprehensive somatic genotyping study, profile, which has enrolled and sequenced tumor from over 400 pediatric patients. In terms of clinical trials for sarcoma, I am Vice Chair of the Bone Tumor Committee of the Children’s Oncology Group (COG), the principal North American pediatric oncology clinical trials consortium. I am the Study Chair of COG protocol “AOST1321, a phase II study of Denosumab in Recurrent Osteosarcoma” and the institutional PI of 5 phase II, phase III and biology protocols for bone sarcomas and GIST.
Clinical Interests
Ewing sarcoma
Gastrointestinal stromal tumor
Osteosarcoma
Personalized medicine
Sarcomas
Clinical Interests
Ewing sarcoma
Gastrointestinal stromal tumor
Osteosarcoma
Personalized medicine
Sarcomas
研究兴趣
论文共 284 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Aubrey K. Hubbard,Weiyin Zhou, Carrie Boyce,Javed Khan, Melissa M. Hudson,Kirsten K. Ness,Zhaoming Wang,Katherine A. Janeway,Philip J. Lupo,Lindsay M. Morton, Stephen J. Chanock, Thomas G. Grünewald,
Cancer Researchno. 6_Supplement (2024): 6148-6148
Lisa Mirabello,Laura E. Egolf,Bin Zhu,D. Matthew Gianferante, Kevin Wang,Shengchao Alfred Li,Mitchell J. Machiela,Logan G. Spector,Joshua D. Schiffman,Aniko Sabo, Alexander Renwick,Bailey Martin-Giacalone,
Cancer Researchno. 6_Supplement (2024): 775-775
Safia K. Ahmed, Odion Binitie,Mark D. Krailo,Allen Buxton,Daniel J. Indelicato,Alexandra Callan, Alexander Christ,Paul J. Chuba,Helen Ruth Nadel,Bruce Pawel,Richard Greg Gorlick,Damon R. Reed,
JOURNAL OF CLINICAL ONCOLOGYno. 16 (2023): 11529-11529
引用0浏览0引用
0
0
Journal of the National Cancer Institute (2023)
引用3浏览0WOS引用
3
0
Journal of cutaneous pathology (2023)
PEDIATRIC BLOOD & CANCERno. S6 (2023): e30583-e30583
crossref(2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn