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My group applies an interdisciplinary approach that combines biophysics, molecular/cell biology and medicine to quantitatively investigate and model the relation between the DNA organization in the nucleus into chromatin and the regulation of gene expression. Both in vitro and in vivo experiments are conducted using scanning/atomic force microscopy imaging, analytical ultracentrifugation and fluorescence spectroscopy/microscopy approaches to elucidate how chromatin assembly, conformation, dynamics and accessibility are controlled. Furthermore, various contributions to the modeling and quantitative analysis of the kinetics of chromatin assembly and the chromatin fiber organization have been made.
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论文共 276 篇作者统计合作学者相似作者
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Anne Rademacher, Alik Huseynov, Michele Bortolomeazzi, Sina Jasmin Wille, Sabrina Schumacher, Pooja Sant, Denise Keitel, Konstantin Okonechnikov, David Ghasemi, Kristian Pajtler, Jan-Philipp Mallm,Karsten Rippe
biorxiv(2024)
Cancer Researchno. 6_Supplement (2024): 14-14
Nature Communicationsno. 1 (2024): 269-269
Journal of hepatologyno. 2 (2023): 296-+
M. R. Hakobyan,Jens Langstein, Emely Kleinert,Maximilian Schönung,Mark Hartmann, H. Rohdjeß,Sina Staeble,Rainer Claus,Lars Bullinger, Christopher C. Oakes,Karsten Rippe,Stefan Fröhling,
HemaSphereno. S3 (2023): e3395424-e3395424
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CLINICAL LYMPHOMA MYELOMA & LEUKEMIA (2023): S156-S156
Christian Bundschuh,Niklas Weidner,Julian Klein, Tobias Rausch, Nayara Azevedo, Anja Telzerow,Jan-Philipp Mallm,Heeyoung Kim,Simon Steiger,Isabelle Seufert,Kathleen Börner,Katharina Bauer,
medRxiv (Cold Spring Harbor Laboratory) (2023)
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Cancer cellno. 4 (2023): 711-725.e6
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