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The transition from fetal to independent life involves many adaptive processes in metabolism. Adaptation at this time has important impacts on both short term and long term health. In the NICU we try to control this environment to optimize the short term care but as yet do not fully understand the implications of what we do for long term health. At this time it is not uncommon for babies to have problems with glucose control. In the preterm infant the combination of hyperglycaemia, insulin deficiency and catabolism can be a challenge to manage clinically and may also have implications for both short and long term health. Interestingly babies born preterm, small for gestational age and large for gestational age are all at long term risk of impaired glucose tolerance which is a risk factor for type 2 diabetes. We are interested in exploring areas to improve our short term clinical management and investigating the long term impact on neurocognitive and metabolic outcomes of these babies.
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Diabetes Technology & Therapeutics (2023)
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Research Square (Research Square)no. 1 (2023): 1-8
Frontiers in pediatrics (2023): 1236258
LANCET CHILD & ADOLESCENT HEALTHno. 5 (2021): E16-E16
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