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个人简介
Julie Goodwin, MD
Associate Professor of Pediatrics (Nephrology); Fellowship Program Director
Research Summary
The glucocorticoid receptor is found in nearly every cell type. It is the receptor for the body's endogenous steroid (cortisol) as well as for the many synthetic steroids (prednisone, dexamethasone) that are used therapeutically for a variety of conditions. Studies have clearly shown that this receptor has tissue-specific functions and that loss of the receptor in specific tissuess produces profound and unexpected phenotypes. I am interested in determining the role of this receptor in the endothelium, and more recently, in podocytes, the specialized cells which maintain the filtration barrier in the kdiney.
Specialized Terms: Glucocorticoid-induced hypertension; Vascular endothelial glucocorticoid receptor; Steroids and sepsis; Atherosclerosis; Podocyte glucocorticoid receptor and nephrotic syndrome
Associate Professor of Pediatrics (Nephrology); Fellowship Program Director
Research Summary
The glucocorticoid receptor is found in nearly every cell type. It is the receptor for the body's endogenous steroid (cortisol) as well as for the many synthetic steroids (prednisone, dexamethasone) that are used therapeutically for a variety of conditions. Studies have clearly shown that this receptor has tissue-specific functions and that loss of the receptor in specific tissuess produces profound and unexpected phenotypes. I am interested in determining the role of this receptor in the endothelium, and more recently, in podocytes, the specialized cells which maintain the filtration barrier in the kdiney.
Specialized Terms: Glucocorticoid-induced hypertension; Vascular endothelial glucocorticoid receptor; Steroids and sepsis; Atherosclerosis; Podocyte glucocorticoid receptor and nephrotic syndrome
研究兴趣
论文共 44 篇作者统计合作学者相似作者
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Rizwana Afroz,Julie E. Goodwin
BIOMEDICINESno. 2 (2024): 276
Swayam Prakash Srivastava,Han Zhou, Rachel Shenoi, Myshal Morris,Leigh Goedeke,Barani Kumar Rajendran,Ocean Setia,Binod Aryal, Keizo Kanasaki,Daisuke Koya,Alan Dardik, Thomas Bell,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Arteriosclerosis, Thrombosis, and Vascular Biologyno. Suppl_1 (2023)
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Kidney360no. 3 (2023): 387-392
Frontiers in endocrinology (2023): 1251897
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
JVS-Vascular Science (2023): 100147
Mohammad Shohel Akhter,Julie Elizabeth Goodwin
International journal of molecular sciencesno. 18 (2023)
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Pediatric Hypertensionpp.1-21, (2022)
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