Josef Lazar - Charles University in Prague

基本信息

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个人简介

I originally wanted to develop a genetically encoded fluorescent sensor of cell membrane voltage, to image the electrical activity of neurons. That's why we developed two-photon polarization microscopy (and related techniques), which can see MUCH MORE than just membrane voltage. We now develop biosensors for polarization microscopy and use them to image activity of GPCRs, RTKs, and other proteins. To do it well, we study properties of fluorescent proteins, write software, and build microscopes.

研究兴趣

论文共 290 篇作者统计合作学者相似作者

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Country Wide Shared FibreBased Infrastructure for Dissemination of Precise Time, Coherent Optical Frequency with Vibration Sensing

Josef Vojtech, Tomas Novak, Elisabeth Andriantsarazo,Vladimir Smotlacha, Ondrej Havlis,Rudolf Vohnout, Michal Spacek,Martin Slapak, Lada Altmannova, Radek Velc,Petr Pospisil, Jan Kundrat,Martin Cizek,Jan Hrabina,Simon Rerucha,Lenka Pravdova,Josef Lazar,Ondrej Cip,Jaroslav Roztocil

arxiv（2025）

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Novel Genetically Encoded Biosensors for Functional Imaging of Cell Signaling by Polarization Microscopy

Paul Miclea,Vendula Nagy-Marková, Alina Sakhi,Alexey Bondar,Josef Lazar

BIO Web of Conferences (2024): 14003

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A Genetically-Encoded Nanobody Sensor Reveals Conformational Diversity in Β-Arrestins Orchestrated by Distinct Seven Transmembrane Receptors

Parishmita Sarma,Vendula Nagy Marková, Nashrah Zaidi,Annu Dalal,Sudha Mishra,Manish K. Yadav,Gargi Mahajan, Nabarun Roy,Paul Miclea,Josef Lazar,Arun K. Shukla

biorxiv（2024）

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Characterising and Tackling Thermally Induced Zero-Drift in Displacement Measuring Interferometry Using Temperature-Controlled Enclosure

Simon Rerucha,Miroslava Hola,Ondrej Cip,Josef Lazar,Jindrich Oulehla,Bretislav Mikel

MEASUREMENT SCIENCE AND TECHNOLOGY（2024）

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Correction of Phase Drifts in Two-Wavelength Digital Holographic Microscopy Using Secondary Reference Waves

Šarbort Martin,Čížek Martin, Pavelka Jan,Lazar Josef

EPJ Web of Conferences (2024): 02006

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A Widely Applicable Novel Design of Genetically Encoded Fluorescent Probes for Imaging Cell Signaling

Josef Lazar,Paul S. Miclea,Vendula Markova, Alina Sakhi,Petro Khoroshyy,Alexey Bondar,Jitka Myskova

Biophysical Journalno. 3 (2024): 553a-553a

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Thermally Compensated Common-Path Differential Interferometer with Reduced Long-Term Zero-Drifts

Simon Rerucha,Miroslava Hola,Jindrich Oulehla,Josef Lazar,Bretislav Mikel,Ondrej Cip

MEASUREMENT SCIENCE AND TECHNOLOGYno. 9 (2024)

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National Infrastructure for Dissemination of Precise Time and Ultra-stable Optical Frequency Also Aiming to Connect Quantum Sources - CITAF

Josef Vojtech,Vladimir Smotlacha,Ondrej Havlis,Rudolf Vohnout, Michal Spacek,Tomas Novak,Elisabeth Andriantsarazo,Martin Slapak,Lada Altmannova,Radek Velc,Petr Pospisil,Jan Kundrat,Martin Cizek,Jan Hrabina,Simon Rerucha,Lenka Pravdova,Josef Lazar,Ondrej Cip,Alexander Kuna,Jaroslav Roztocil

QUANTUM OPTICS AND PHOTON COUNTING 2023 (2023)

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Towards Shared Fiber Dissemination Infrastructure for Precise Time, Coherent Optical Frequency and Entanglement Transfers with Sensing Option

Infrared Remote Sensing and Instrumentation XXXI (2023)

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National Infrastructure for Dissemination of Precise Time and Coherent Ultra-stable Op-tical Frequency - CITAF

Josef Vojtech,Vladimir Smotlacha,Ondrej Havlis,Martin Slapak,Lada Altmannova,Jan Kundrat,Sarbojeet Bhowmick,Rudolf Vohnout,Radek Velc,Petr Pospisil,Martin Cizek,Jan Hrabina,Simon Rerucha,Lenka Pravdova,Josef Lazar,Ondrej Cip,Alexander Kuna,Jaroslav Roztocil

Proceedings of the annual Precise Time and Time Interval (PTTI) Systems and Applications Meeting/Proceedings of a meeting - Precise Time and Time Interval (PTTI) Systems and Applications Meeting (2022)

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