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His team pioneered the development of artificial white blood cells, called artificial antigen-presenting cells (aAPCs), which show promise in training animals' immune systems to fight diseases such as cancer. Using nano-aAPCs, his team recently trained the immune systems of mice to fight melanoma.
His lab’s current projects include studying the biophysical, genetic and environmental control of T cell receptor organization.
Dr. Schneck’s research focuses on the basic mechanisms that control immune responses. Specifically, he studies how cytotoxic T-cells, known as killer T cells—cells that help eliminate infections or cancers—get activated, recognize their targets and get turned off again. His team focuses on how to manipulate the immune system with the hopes of designing improved anti-cancer therapies by ramping up the immune system, or treating autoimmune disease and transplant patients with better immune system suppression.
His lab’s current projects include studying the biophysical, genetic and environmental control of T cell receptor organization.
Dr. Schneck’s research focuses on the basic mechanisms that control immune responses. Specifically, he studies how cytotoxic T-cells, known as killer T cells—cells that help eliminate infections or cancers—get activated, recognize their targets and get turned off again. His team focuses on how to manipulate the immune system with the hopes of designing improved anti-cancer therapies by ramping up the immune system, or treating autoimmune disease and transplant patients with better immune system suppression.
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论文共 121 篇作者统计合作学者相似作者
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Natalie K. Livingston,John W. Hickey, Hajin Sim,Sebastian F. Salathe,Joseph Choy,Jiayuan Kong,Aliyah B. Silver,Jessica L. Stelzel, Mary O. Omotoso, Shuyi Li,Worarat Chaisawangwong, Sayantika Roy,
Savannah E. Est-Witte,Sydney R. Shannon,Dennis H. Gong, Kaitlyn G. Calabresi, Jawaun J. Harris,Kaitlyn Storm,Edwin J. Yoo,Ariel Isser, Vivek P. Jani,Natalie K. Livingston, Mary O. Omotoso,Kelly Rhodes,
Nano Researchpp.1-13, (2024)
Current protocolsno. 2 (2024): e976-e976
Acta biomaterialia (2023): 187-197
Yining Zhu, Jingyao Ma, Ruochen Shen,Jinghan Lin, Shuyi Li,Xiaoya Lu,Jessica L. Stelzel,Jiayuan Kong,Leonardo Cheng,Ivan Vuong,Zhi-Cheng Yao, Christine Wei,
Journal of Immunologyno. 1 (2023): 250.12-250.12
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Worarat Chaisawangwong, Hanzhi Wang,Theodore Kouo,Sebastian F. Salathe,Ariel Isser,Joan Glick Bieler, Maya L. Zhang,Natalie K. Livingston, Shuyi Li, Joseph J. Horowitz,Ron E. Samet,Israel Zyskind,
JCI INSIGHTno. 18 (2022)
Jian Lu,Guobing Chen, Arina Sorokina,Thomas Nguyen,Tonya Wallace,Cuong Nguyen,Christopher Dunn, Stephanie Wang, Samantha Ellis,Guixin Shi,Julia McKelvey,Alexei Sharov,
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