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The role of voltage gated potassium channels in healthy and diseased tissues
The overall goal of my research is to understand the role of voltage gated potassium channels in normal health and human disease. I have a long-standing interest in the role of potassium channels, particularly hERG (Kv11), in cardiac repolarization and how dysfunction leads to arrhythmias and sudden cardiac death. More recently, I have also become interested in the role of hEAG (Kv10), a close relative of hERG, in cancer. We use a combination of electrophysiology, molecular biology, protein biochemistry and structure biology techniques to study ion channels in native tissues and cell lines.
The role of voltage gated potassium channels in healthy and diseased tissues
The overall goal of my research is to understand the role of voltage gated potassium channels in normal health and human disease. I have a long-standing interest in the role of potassium channels, particularly hERG (Kv11), in cardiac repolarization and how dysfunction leads to arrhythmias and sudden cardiac death. More recently, I have also become interested in the role of hEAG (Kv10), a close relative of hERG, in cancer. We use a combination of electrophysiology, molecular biology, protein biochemistry and structure biology techniques to study ion channels in native tissues and cell lines.
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Biophysical Journalno. 3 (2018): 294a
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Nature Communicationsno. 1 (2018): 1-1
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