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个人简介
Current Research and Scholarly Interests
My work is trying to optimize the chances of getting more reliable, trustworthy, and useful research. I have worked in the fields of evidence-based medicine, clinical investigation, clinical and molecular epidemiology, clinical research methodology, empirical research methods, statistics, and genomics. I have a strong interest in meta-research and in large-scale evidence (in particular randomized trials and meta-analyses) and in appraisal and control of diverse biases in biomedical research and beyond. I am interested in developing and applying new research methods, and in the interdisciplinary enhancement of existing research methods for study design and analysis. Some of my most influential papers in terms of citations are those addressing issues of reproducibility, replication validity, biases in biomedical research and other fields, research synthesis methods, extensions of meta-analysis, genome-wide association studies and agnostic evaluation of associations, and validity of randomized trials and observational research. I have also designed, steered and participated in influential randomized trials (in particular, the major trials that changed decisively the management and outcome of HIV infection, but also trials in nephrology, and in antibiotic use in the community), and large international consortia that have helped transform the efficiency of research in diverse fields of genomic, molecular and clinical epidemiology. I enjoy working with a diverse array of colleagues from very diverse disciplines and to have an opportunity to learn from both senior and junior investigators, and particularly students at all levels.
研究兴趣
论文共 1274 篇作者统计合作学者相似作者
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EUROPEAN JOURNAL OF CLINICAL INVESTIGATIONno. 3 (2024): e14136-e14136
arxiv(2024)
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DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGYno. 4 (2024): 415-421
BMJ OPENno. 1 (2024): e076675-e076675
NEJM evidenceno. 3 (2024): EVIDe2300322-EVIDe2300322
Reference Module in Biomedical Sciences (2024)
BMJ EVIDENCE-BASED MEDICINEno. 1 (2024): 6-9
JAMAno. 4 (2024): 354-355
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