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Research in this laboratory is aimed at understandingthe pathogenesis of chronic infection with Epstein-Barr Virus [EBV] and Human Immunodeficiency Virus [HIV]. Studies of EBV are focused on the nature of the immune response which controls but does not eradicate viral replication and the nature of the immune defect which results in the X-linked lymphoproliferative syndrome. Studies of HIV are focused on the elucidation and characterization of HIV gene mutations which result in infections associated with long term control of viral replication and/or lack of disease progression.
Experimental therapeutic and preventative vaccine approaches are also being studied. These include combination antiretroviral agents to interrupt viral replication and recombinant vector or live attenuated vaccines to prevent HIV-1 infection. Of particular interest is the development of therapeutics and vaccine regimens which can be used in the developing world to interrupt maternal to child transmission.
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The Australasian journal of dermatology (2023)
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Jaime E Hale,Craig D Platt,Francisco A Bonilla,Beverly N Hay,John L Sullivan,Alicia M Johnston,Mark S Pasternack, Paul E Hesterberg,H Cody Meissner,Ellen R Cooper, Sara Barmettler,Jocelyn R Farmer,
The Journal of Allergy and Clinical Immunology: In Practiceno. 5 (2021): 2060-2067.e2
new interfaces for musical expression (2021)
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