Professor McNeil has a research background in epidemiology and public health. His research activities involve the application of epidemiological methods to clinical medicine and public health problems. Key points include A clinical trial plan initiated by researchers was established, including MAVET and VECAT trials of vitamin E funded by NHMRC and MAVET trials of folic acid supplementation for renal failure. The United States-Australia NIH-funded joint trial of low-dose aspirin ASPREE for the elderly, which is the largest preventive trial in Australia, is mainly based on the "ANBP2" method. All kinds of sub-research will ensure that ASPREE will become the main international resource for the elderly research. Make a drug epidemiological research plan to identify people at risk of serious heterogeneous adverse drug reactions (ADR). Lead a team that successfully applied for NHMRC Center of Excellence in Clinical Research on Patient Safety. This has become Australia's main registered science center.