He completed his undergraduate studies in Adelaide, and his postgraduate training in Melbourne and Boston, taking up his current position in 1988.
Project 1. Coronary artery spasm
The research group has recently found that coronary artery spasm, a common cause of cardiac crises, is due to interactions between activated platelets and the vascular surface of the coronary blood vessels, with poor vascular and platelet responsiveness to nitric oxide. We have preliminary data on the underlying mechanisms whereby coronary spasm presents with episodic crises, and wish to validate these pilot data, simultaneously turning the information into the bases for new therapeutic options for these patients, and also possibly for other patients with angina.