John G. Laffey

Department of Anaesthesia, Galway University Hospitals, Galway, Ireland|Department of Anaesthesia, Clinical Sciences Institute, National University of Ireland, Galway, Ireland

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Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism.

Shahd Horie, Sean Gaynard, Mary Murphy,Frank Barry, Michael Scully, Daniel O'Toole,John G Laffey

Intensive care medicine experimental, no. 1 (2020): 8

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β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects - Implications for coronavirus disease (COVID-19) immunotherapies.

Emma J Murphy, Claire Masterson, Emanuele Rezoagli,Daniel O'Toole, Ian Major, Gary D Stack, Mark Lynch,John G Laffey,Neil J Rowan

The Science of the total environment, (2020): 139330

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The authors reply.

Tài Pham,John Laffey,Giacomo Bellani,Laurent Brochard,Frank van Haren

Critical care medicine, no. 5 (2020)

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Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis.

Adrien Carla,Bruno Pereira, Hanifa Boukail, Jules Audard, Nathalie Pinol-Domenech, Manuela De Carvalho,Raiko Blondonnet, Ruoyang Zhai,Dominique Morand, Céline Lambert,Vincent Sapin,Lorraine B Ware

Respiratory research, no. 1 (2020): 81

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Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study.

Fabiana Madotto, Emanuele Rezoagli, Tài Pham, Marcello Schmidt, Bairbre McNicholas, Alessandro Protti, Rakshit Panwar,Giacomo Bellani,Eddy Fan,Frank van Haren,Laurent Brochard,John G Laffey

Critical care (London, England), no. 1 (2020): 125

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Missed or delayed diagnosis of ARDS: a common and serious problem

Giacomo Bellani,Tài Pham,John G. Laffey

Intensive Care Medicine, pp.1-4, (2020)

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Umbilical cord-derived CD362 + mesenchymal stromal cells for E. coli pneumonia: impact of dose regimen, passage, cryopreservation, and antibiotic therapy.

Shahd Horie, Claire Masterson, Jack Brady, Paul Loftus, Emma Horan,Lisa O'Flynn,Steve Elliman,Frank Barry,Timothy O'Brien,John G Laffey,Daniel O'Toole

Stem cell research & therapy, no. 1 (2020): 116

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Patterns of use of adjunctive therapies in patients with early moderate- severe Acute Respiratory Distress syndrome: Insights from the LUNG SAFE Study.

Abhijit Duggal, Emanuele Rezoagli,Tai Pham, Bairbre A McNicholas,Eddy Fan,Giacomo Bellani,Gordon Rubenfeld,Antonio Pesenti,John G Laffey

Chest, (2020)

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The worldwide assessment of separation of patients from ventilatory assistance (WEAN SAFE) ERS Clinical Research Collaboration

Leo Heunks,Giacomo Bellani,Tài Pham,Tài Pham,Laurent Brochard,Laurent Brochard,John G. Laffey,John G. Laffey

European Respiratory Journal, no. 3 (2019): 1802228

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Modulating the distribution and fate of exogenously delivered MSCs to enhance therapeutic potential: knowns and unknowns

Claire H. Masterson, Gerard F. Curley,John G. Laffey

Intensive Care Medicine Experimental, (2019)

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Extracellular Vesicles from Interferon-γ-primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli-induced Acute Lung Injury in Rats.

Amir K Varkouhi,Mirjana Jerkic, Lindsay Ormesher, Stéphane Gagnon, Sakshi Goyal, Razieh Rabani,Claire Masterson, Chris Spring,Paul Z Chen,Frank X Gu,Claudia C Dos Santos,Gerard F Curley

Anesthesiology, pp.1, (2019)

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Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats.

Mirjana Jerkic, Stéphane Gagnon, Razieh Rabani, Taylor Ward-Able, Claire Masterson,Gail Otulakowski,Gerard F Curley,John Marshall,Brian P Kavanagh,John G Laffey

Anesthesiology, pp.1, (2019)

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Nebulized Mesenchymal Stem Cell Derived Conditioned Medium Retains Antibacterial Properties Against Clinical Pathogen Isolates.

Sean D McCarthy, Elizabeth Horgan, Areeba Ali, Claire Masterson,John G Laffey, Ronan MacLoughlin,Daniel O'Toole

Journal of aerosol medicine and pulmonary drug delivery, (2019)

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What's new in airway management of the critically ill.

Vincenzo Russotto, Sheila N Myatra,John G Laffey

Intensive care medicine, pp.1-4, (2019)

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Why translational research matters: proceedings of the third international symposium on acute lung injury translational research (INSPIRES III).

Nicole P Juffermans,Marcus Schultz, Lieuwe D Bos, Oscar Penuelas,John Laffey, Jose A Lorente

Intensive care medicine experimental, no. Suppl 1 (2019): 40

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Declining Mortality in Patients With Acute Respiratory Distress Syndrome: An Analysis of the Acute Respiratory Distress Syndrome Network Trials.

Zhongheng Zhang,Peter Markus Spieth,Davide Chiumello, Hemant Goyal,Antoni Torres,John G Laffey, Yucai Hong

Critical care medicine, no. 3 (2019): 315-323

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Demographics, management and outcome of women and men with Acute Respiratory Distress Syndrome in the LUNG SAFE prospective cohort study.

Bairbre A McNicholas,Fabiana Madotto, Tài Pham, Emanuele Rezoagli,Claire H Masterson,Shahd Horie,Giacomo Bellani,Laurent Brochard,John G Laffey

The European respiratory journal, pp.1900609, (2019)

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Overexpression of IL-10 Enhances the Efficacy of Human Umbilical-Cord-Derived Mesenchymal Stromal Cells in E. coli Pneumosepsis.

Mirjana Jerkic,Claire Masterson, Lindsay Ormesher, Stéphane Gagnon, Sakshi Goyal, Razieh Rabani,Gail Otulakowski,Haibo Zhang,Brian P Kavanagh,John G Laffey

Journal of clinical medicine, no. 6 (2019): 847

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Impact of Early Acute Kidney Injury on Management and Outcome in Patients With Acute Respiratory Distress Syndrome: A Secondary Analysis of a Multicenter Observational Study.

Bairbre A McNicholas, Emanuele Rezoagli, Tài Pham,Fabiana Madotto, Elsa Guiard,Vito Fanelli,Giacomo Bellani,Matthew D Griffin,Marco Ranieri,John G Laffey

Critical care medicine, pp.1, (2019)

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Effects of gastro-oesophageal reflux and pulmonary micro-aspiration in bronchiectasis

Melissa Mcdonnell,Jeeban Das,Daniel O'Toole, Adil Aldrahani,Bernard Verdon,Matthew Wilcox,Jeffrey Pearson,James Lordan,Anthony De Soyza, Najwa Sousi,James Chalmers,John Laffey

European Respiratory Journal, (2018)

Cited by1Bibtex

Emanuele Rezoagli, Bairbre McNicholas, Peter Moran,John G Laffey

American journal of respiratory and critical care medicine, (2018)

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Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database.

Andrew J Boyle,Fabiana Madotto,John G Laffey,Giacomo Bellani,Tài Pham,Antonio Pesenti,B Taylor Thompson,Cecilia M O'Kane,Adam M Deane,Daniel F McAuley

Critical care (London, England), no. 1 (2018): 268

Cited by1WOSBibtex

Sepsis Therapies: Insights from Population Health to Cellular Therapies and Genomic Medicine

Emanuele Rezoagli, Bairbre McNicholas,Peter Moran,John G. Laffey

American Journal of Respiratory and Critical Care Medicine, no. 12 (2018): 1570-1572

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III. REGIONAL ANESTHESIA Using Activity Trackers to Quantify Postpartum Ambulation: A Prospective Observational Study of Ambulation After Regional Anesthesia and Analgesia Interventions

J. Ma, R. Martin, B. Chan, M. Gofeld, M.P. Geary,J.G. Laffey,F.W. Abdallah

Obstetric Anesthesia Digest, no. 4 (2018): 223-224

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Negative trials in critical care: why most research is probably wrong.

John G Laffey,Brian P Kavanagh

The Lancet. Respiratory medicine, (2018)

Cited by1WOSBibtex

Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study.

Frank van Haren,Tài Pham,Laurent Brochard,Giacomo Bellani,John Laffey,Martin Dres,Eddy Fan, Ewan C Goligher,Leo Heunks,Joan Lynch,Hermann Wrigge,Danny McAuley

Critical care medicine, (2018)

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Syndecan-2-positive, Bone Marrow-derived Human Mesenchymal Stromal Cells Attenuate Bacterial-induced Acute Lung Injury and Enhance Resolution of Ventilator-induced Lung Injury in Rats.

Claire Masterson,James Devaney,Shahd Horie,Lisa O'Flynn,Laura Deedigan,Steve Elliman,Frank Barry,Timothy O'Brien,Daniel O'Toole,John G Laffey

Anesthesiology, (2018)

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Cell therapy in acute respiratory distress syndrome

Shahd Horie, Hector Esteban Gonzalez,John G. Laffey,Claire Masterson

Journal of Thoracic Disease, no. 9 (2018): 5607-5620

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Research in extracorporeal life support: a call to action.

Daniel Brodie,Vincent Jean-Louis,Laurent J Brochard,Alain Combes,Niall D Ferguson,Carol L Hodgson,John G Laffey,Alain Mercat,Antonio Pesenti,Michael Quintel,Arthur S Slutsky,V Marco Ranieri

Chest, (2018)

Cited by2WOSBibtex

The Randomized Educational Acute Respiratory Distress Syndrome Diagnosis Study: A Trial to Improve the Radiographic Diagnosis of Acute Respiratory Distress Syndrome.

Shannon L Goddard,Gordon D Rubenfeld,Venika Manoharan, Shelly P Dev,John Laffey,Giacomo Bellani,Tai Pham,Eddy Fan

Critical care medicine, (2018)

Cited by2WOSBibtex

Mesenchymal stem cells enhance NOX2-dependent reactive oxygen species production and bacterial killing in macrophages during sepsis

Razieh Rabani, Allen Volchuk,Mirjana Jerkic, Lindsay Ormesher, Linda Garces-Ramirez,Johnathan Canton, Claire Masterson, Stephane Gagnon,Kate Tatham,Kate Tatham,John Marshall,John Marshall

European Respiratory Journal, no. 4 (2018): 1702021

Cited by3Bibtex

Immunocompromised patients with acute respiratory distress syndrome: secondary analysis of the LUNG SAFE database.

Andrea Cortegiani,Fabiana Madotto,Cesare Gregoretti,Giacomo Bellani,John G Laffey,Tai Pham,Frank Van Haren,Antonino Giarratano,Massimo Antonelli,Antonio Pesenti,Giacomo Grasselli

Critical care (London, England), no. 1 (2018): 157

Cited by2WOSBibtex

Should continuous rather than single-injection interscalene block be routinely offered for major shoulder surgery? A meta-analysis of the analgesic and side-effects profiles

L. Vorobeichik,Richard Brull,Richard Brull, R. Bowry, R. Bowry,John G. Laffey,F.W. Abdallah

BJA: British Journal of Anaesthesia, no. 4 (2018): 679-692

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Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries.

Toshikazu Abe,Fabiana Madotto,Tài Pham,Isao Nagata, Masatoshi Uchida,Nanako Tamiya, Kiyoyasu Kurahashi,Giacomo Bellani,John G Laffey

Critical care (London, England), no. 1 (2018): 195

Cited by1WOSBibtex

Is Activity Tracker-Measured Ambulation an Accurate and Reliable Determinant of Postoperative Quality of Recovery? A Prospective Cohort Validation Study.

Faraj Massouh, Rachel Martin, Bokman Chan, Julia Ma, Vikita Patel, Michael P Geary,John G Laffey,Duminda N Wijeysundera,Faraj W Abdallah

Anesthesia and analgesia, (2018)

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Identification and Modulation of Microenvironment is Crucial for Effective MSC Therapy in Acute Lung Injury.

Diana Islam,Yongbo Huang,Vito Fanelli,Luisa Delsedime,Sulong Wu, Julie Khang,Bing Han, Alice Grassi, Manshu Li, Yonghao Xu,Alice Luo, Jianfeng Wu

American journal of respiratory and critical care medicine, (2018)

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Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study.

Fabiana Madotto,Tài Pham,Giacomo Bellani,Lieuwe D Bos, Fabienne D Simonis,Eddy Fan,Antonio Artigas,Laurent Brochard,Marcus J Schultz,John G Laffey

Intensive care medicine, (2018)

Cited by3WOSBibtex

A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk

Melissa J. McDonnell,Melissa J. McDonnell,D. O'Toole,Christopher Ward,Jeffrey P. Pearson,James Lordan,A De Soyza,Michael R. Loebinger,James D. Chalmers,John G. Laffey,John G. Laffey,Robert Rutherford

Respiratory Medicine, (2018): 132-143

Cited by1Bibtex

Emanuele Rezoagli,Claire H Masterson, Sean D McCarthy,John G Laffey

American journal of respiratory cell and molecular biology, (2018)

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Mesenchymal stem cells enhance NOX2 dependent ROS production and bacterial killing in macrophages during sepsis.

Razieh Rabani, Allen Volchuk, Mirjana Jerkic, Lindsay Ormesher, Linda Garces-Ramirez, Johnathan Canton, Claire Masterson, Stephane Gagnon, Kate C Tatham,John Marshall,Sergio Grinstein,John G Laffey

The European respiratory journal, (2018)

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Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury.

Nala Shologu, Michael Scully,John G Laffey,Daniel O'Toole

International journal of molecular sciences, no. 10 (2018)

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The intensive care medicine research agenda for airways, invasive and noninvasive mechanical ventilation

Samir Jaber,Giacomo Bellani,Lluis Blanch,Lluis Blanch,Alexandre Demoule,Andrés Esteban,Luciano Gattinoni,Claude Guérin,Nicholas S. Hill,John G. Laffey,Salvatore Maurizio Maggiore,Jordi Mancebo

Intensive Care Medicine, no. 9 (2017): 1352-1365

Cited by7Bibtex

Correction to: Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study.

John G Laffey,Giacomo Bellani,Tài Pham,Eddy Fan,Fabiana Madotto,Ednan K Bajwa,Laurent Brochard, Kevin Clarkson,Andres Esteban,Luciano Gattinoni,Frank van Haren,Leo M Heunks

Intensive care medicine, no. 1 (2017): 157-165

Cited by1WOSBibtex

Impact of a Fully Controlled Ventilation in the First Days of Ards: an Ancillary Analysis of The Lung Safe Study

T Pham,J Laffey, G Bellani, E Fan,F Madotto,L Heunks, E Goligher, M Dres, J Lynch, H Wrigge, D Mcauley,L Brochard

american thoracic society international conference, (2017)

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Using Activity Trackers to Quantify Postpartum Ambulation: A Prospective Observational Study of Ambulation after Regional Anesthesia and Analgesia Interventions.

Julia Ma, Rachel Martin, Bokman Chan, Michael Gofeld, Michael P Geary,John G Laffey,Faraj W Abdallah

Anesthesiology, (2017)

Cited by1WOSBibtex

Lessons to learn from epidemiologic studies in ARDS.

Bairbre A McNicholas, Grainne M Rooney,John G Laffey

Current opinion in critical care, (2017)

Cited by1WOSBibtex

Suprascapular and Interscalene Nerve Block for Shoulder SurgeryA Systematic Review and Meta-analysis

Nasir Hussain, Ghazaleh Goldar, Neli Ragina,Laura Banfield,John G. Laffey,Faraj W. Abdallah

Anesthesiology, no. 6 (2017): 998-1013

Cited by8Bibtex

Reply: “Could Noninvasive Ventilation Failure Rates Be Underestimated in the LUNG SAFE Study?” and “High-Flow Oxygen, Positive End-Expiratory Pressure, and the Berlin Definition of Acute Respiratory Distress Syndrome: Are They Mutually Exclusive?”

Giacomo Bellani,Fabiana Madotto,Tài Pham,Eddy Fan,John G. Laffey

American Journal of Respiratory and Critical Care Medicine, no. 3 (2017): 397-398

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A comparison of videolaryngoscopes for tracheal intubation in predicted difficult airway: a feasibility study.

Maria Vargas,Antonio Pastore,Fulvio Aloj,John G Laffey,Giuseppe Servillo

BMC anesthesiology, no. 1 (2017): 25

Cited by1WOSBibtex

Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome. Insights from the LUNG SAFE Study.

Giacomo Bellani,John G Laffey,Tài Pham,Fabiana Madotto,Eddy Fan,Laurent Brochard,Andres Esteban,Luciano Gattinoni,Vesna Bumbasirevic,Lise Piquilloud,Frank van Haren,Anders Larsson

American journal of respiratory and critical care medicine, no. 1 (2017): 67-77

Cited by47WOSBibtex

Stem Cell-based Therapies for Sepsis.

Colm Keane,Mirjana Jerkic,John G Laffey

Anesthesiology, (2017)

Cited by4WOSBibtex

Consistent ARDS Endotypes Are Identified Using Minimal Data from a United Kingdom Clinical Trial

Carolyn S. Calfee, K. R. Delucchi,Michael A. Matthay, J. Hackett,Manu Shankar-Hari,Christopher McDowell,John G. Laffey,John G. Laffey,Cecilia O'Kane,Daniel F. McAuley

American Journal of Respiratory and Critical Care Medicine, (2017)

Cited by1Bibtex

Noninvasive mechanical ventilation in early acute respiratory distress syndrome.

Alice Grassi,Giuseppe Foti,John G Laffey,Giacomo Bellani

Polish archives of internal medicine, (2017)

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Continued under-recognition of acute respiratory distress syndrome after the Berlin definition: What is the solution?

John G. Laffey,Tài Pham,Giacomo Bellani

Current Opinion in Critical Care, no. 1 (2017): 10-17

Cited by2Bibtex

Cryopreserved, Xeno-Free Human Umbilical Cord Mesenchymal Stromal Cells Reduce Lung Injury Severity and Bacterial Burden in Rodent Escherichia coli-Induced Acute Respiratory Distress Syndrome.

Gerard F Curley,Mirjana Jerkic, Steve Dixon, Grace Hogan,Claire Masterson,Daniel O'Toole,James Devaney,John G Laffey

Critical care medicine, no. 2 (2017)

Cited by8WOSBibtex

Some remaining important questions after LUNG SAFE

Didier Dreyfuss,Stéphane Gaudry,Fabiana Madotto,John G. Laffey

Intensive Care Medicine, no. 4 (2017): 598-599

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Fifty Years of Research in ARDS.Insight into Acute Respiratory Distress Syndrome. From Models to Patients

John G. Laffey,Brian P. Kavanagh

American Journal of Respiratory and Critical Care Medicine, no. 1 (2017): 18-28

Cited by14Bibtex

Etiologies, diagnostic work-up and outcomes of acute respiratory distress syndrome with no common risk factor: a prospective multicenter study.

Nicolas de Prost,Tài Pham,Guillaume Carteaux,Armand Mekontso Dessap,Christian Brun-Buisson,Eddy Fan,Giacomo Bellani,John Laffey,Alain Mercat,Laurent Brochard,Bernard Maître

Annals of intensive care, no. 1 (2017): 69

Cited by6WOSBibtex

Fifty Years of Research in ARDS.Cell-based Therapy for Acute Respiratory Distress Syndrome. Biology and Potential Therapeutic Value

John G. Laffey,Michael A. Matthay

American Journal of Respiratory and Critical Care Medicine, no. 3 (2017): 266-273

Cited by20Bibtex

Simvastatin for patients with acute respiratory distress syndrome: long-term outcomes and cost-effectiveness from a randomised controlled trial

A. Agus,C. Hulme,R. M. Verghis,C. McDowell, C. Jackson,C. M. O’Kane,J. G. Laffey,D. F. McAuley

Critical Care, no. 1 (2017): 108

Cited by2Bibtex

Statin therapy for acute respiratory distress syndrome: an individual patient data meta-analysis of randomised clinical trials

Myura Nagendran,Daniel F. McAuley,Peter Kruger,Laurent Papazian,Jonathon D. Truwit,John G. Laffey,B. Taylor Thompson,Mike Clarke,Anthony C. Gordon

Intensive Care Medicine, no. 5 (2017): 663-671

Cited by5Bibtex

Incidence of Acute Respiratory Distress Syndrome—Reply

Giacomo Bellani,Tai Pham,John Laffey

JAMA, no. 3 (2016): 347-347

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Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study.

Melissa J. McDonnell,Melissa J. McDonnell,Stefano Aliberti,Stefano Aliberti,Pieter Goeminne,Marcos I. Restrepo,Simon Finch,Alberto Pesci,Lieven Dupont,Thomas C. Fardon,Rob Wilson,Michael R. Loebinger

The Lancet Respiratory Medicine, no. 12 (2016): 969-979

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Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study

John G. Laffey,John G. Laffey,Giacomo Bellani, Tài Pham, Tài Pham,Eddy Fan,Eddy Fan, Fabiana Madotto, Ednan K. Bajwa,Laurent Brochard,Laurent Brochard, Kevin Clarkson

Intensive Care Medicine, no. 12 (2016): 1865-1876

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The ten studies that should be done in ARDS.

Shailesh Bihari,John G Laffey,Andrew D Bersten

Intensive care medicine, no. 5 (2016): 783-786

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Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries

Giacomo Bellani,John G. Laffey,John G. Laffey,Tài Pham,Tài Pham,Eddy Fan,Eddy Fan,Laurent Brochard,Laurent Brochard,Andrés Esteban,Luciano Gattinoni,Frank Van Haren

JAMA, no. 8 (2016): 788-800

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Challenges with PRONE ventilation in ARDS patients: response to comments by Chertoff

Shailesh Bihari,John G. Laffey,Andrew D. Bersten

Intensive Care Medicine, no. 12 (2016): 2124-2125

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Multidimensional severity assessment in bronchiectasis: an analysis of seven European cohorts

Melissa J. McDonnell,Melissa J. McDonnell,Melissa J. McDonnell,Stefano Aliberti,Stefano Aliberti,Pieter Goeminne, Katerina Dimakou, S C Zucchetti, S C Zucchetti,John Davidson,Christopher Ward,John G. Laffey

Thorax, no. 12 (2016): 1110-1118

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Recent insights: mesenchymal stromal/stem cell therapy for acute respiratory distress syndrome

Shahd Horie,John G. Laffey,John G. Laffey

F1000Research, (2016): 1532

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Biotrauma and Ventilator-Induced Lung Injury: Clinical Implications

Gerard F. Curley,Gerard F. Curley,John G. Laffey,John G. Laffey,Haibo Zhang,Haibo Zhang,Arthur S. Slutsky,Arthur S. Slutsky

Chest, no. 5 (2016): 1109-1117

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Multidimensional severity assessment in bronchiectasis - An analysis of 7 European cohorts

Melissa J. McDonnell,Melissa J. McDonnell,Melissa J. McDonnell, Aliberti Stefano,Pieter Goeminne, Katerina Dimakou, Stefano Zuchetti, John Davison,Christopher Ward,John G. Laffey,John G. Laffey,Simon Finch

European Respiratory Journal, (2016)

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Mechanical Ventilation-Associated Lung Fibrosis in Acute Respiratory Distress Syndrome: A Significant Contributor to Poor Outcome

Matteo Parotto, Peter M Spieth,Jesus Villar,Haibo Zhang,Arthur S Slutsky, Nuria E Cabrerabenitez,John G Laffey

Survey of Anesthesiology, (2015)

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INF/IR-8: MIDKINE PLAYS A KEY ROLE IN THE PATHOGENESIS OF ACUTE LUNG INJURY.

Luo Aa, Fanelli,Spieth Pm,Uhlig S,Laffey J, Arthur S. Slutsky,Haibo Zhang

Shock, pp.9, (2015)

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Angiotensin-(1-7) improves oxygenation, while reducing cellular infiltrate and fibrosis in experimental Acute Respiratory Distress Syndrome

Vanessa Zambelli,Giacomo Bellani, Roberto Borsa,F Pozzi,Alice Grassi,Margherita Scanziani,Vittoria Castiglioni,Serge Masson,Alessandra Decio,John G Laffey,Roberto Latini,Antonio Pesenti

Intensive care medicine experimental, no. 1 (2015): 8

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Mechanical Stress and the Induction of Lung Fibrosis via the Midkine Signaling Pathway

Rong Zhang, Ying Pan,Vito Fanelli,Sulong Wu,Alice A Luo, Diana Islam,Bing Han, Pu Mao, Mirna Ghazarian, Wenmei Zeng,Peter M Spieth,Dingyan Wang

American Journal of Respiratory and Critical Care Medicine, (2015)

Cited by18Bibtex

L’oxygénation par membrane extracorporelle pour le traitement d’un SDRA grave lié à une blastomycose: une nouvelle indication de l’ECMO comme traitement de sauvetage?@@@Extracorporeal membrane oxygenation for blastomycosis-related severe ARDS: a new indication as a rescue therapy?

John G Laffey, Neil M Goldenberg, Benjamin E Steinberg

Canadian Journal of Anaesthesia-journal Canadien D Anesthesie, (2015)

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Aerosol-Mediated Delivery of AAV2/6-IκBα Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Rats

Timothy Obrien,John G Laffey,Ronan J Macloughlin, D Otoole, James Devaney, Brendan D Higgins

Human Gene Therapy, (2015)

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What’s new in cell therapies in ARDS?

Shahd Horie,Gerard F. Curley,John G. Laffey

Intensive Care Medicine, pp.1-4, (2015)

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Sepsis protects the myocardium and other organs from subsequent ischaemic/reperfusion injury via a MAPK-dependent mechanism

Criona M Walshe,John G Laffey,Leo G Kevin,Daniel O Toole

Intensive care medicine experimental, no. 1 (2015): 1

Cited by10WOSBibtex

Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury

Mairead Hayes,Gerard F Curley,Claire Masterson,James Devaney,Daniel O Toole,John G Laffey

Intensive care medicine experimental, no. 1 (2015): 29-29

Cited by21WOSBibtex

Tracheostomy procedures in the intensive care unit: an international survey

Maria Vargas,Yuda Sutherasan,Massimo Antonelli,Iole Brunetti, A Corcione,John G Laffey,Christian Putensen,Giuseppe Servillo,Paolo Pelosi

Critical Care, no. 1 (2015): 291

Cited by46Bibtex

Section Editor: Cynthia A. Wong The Analgesic Efficacy of Transversus Abdominis Plane Block After Cesarean Delivery: A Randomized Controlled Trial

John G Mcdonnell, John Carney Mb, C H Maharaj,John G Laffey

(2014)

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Mesenchymal Stem Cell Trials for Pulmonary Diseases: MESENCHYMAL STEM CELL TRIALS FOR PULMONARY DISEASES

Mariana A Antunes,John G Laffey, Patricia R M Rocco,Paolo Pelosi

Journal of Cellular Biochemistry, (2014)

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REVIEW Bench-to-bedside review: Carbon dioxide

Gerard F Curley,John G Laffey, Brian P Kavanagh

(2013)

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The ‘College of Anaesthetists of Ireland’—Delaney Medal Competition Held at College of Anaesthetists of Ireland, Thursday, 14 March 2013, 22 Merrion Square North, Dublin, Ireland

N Murphy, Ajith Vijayan, S Frohlich, S F Sheehan, F O Farrell, John F Boylan, N Conlon, K Srinivasan, M Deighan, L Crowley, K Mckeating, A I Jaura

BJA: British Journal of Anaesthesia, (2013)

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Comparison of the Baska® mask with the single‐use laryngeal mask airway in low‐risk female patients undergoing ambulatory surgery

V Alexiev, A Ochana, D Abdelrahman, Jessica M Coyne, John G Mcdonnell, D Otoole,Patrick J Neligan,John G Laffey

Anaesthesia, (2013)

Cited by5Bibtex

Mesenchymal Stem/Stromal Cells: Opportunities and Obstacles in ARDS

Gerard F Curley, Mairead Hayes,John G Laffey

(2013)

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Predicting the Development of Acute Respiratory Distress Syndrome

John G Laffey,Daniel Talmor

American Journal of Respiratory and Critical Care Medicine, (2013)

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Inhibition Of Pulmonary Nuclear Factor Kappa-B Modulates Acute And Chronic Pneumonia Induced Acute Lung Injury

James Devaney,Gerard F Curley,Timothy O Brien,D Otoole,John G Laffey

(2012)

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Over Expression Of Secretory Leukocyte Protease Inhibitor (SLPI) And Glutathione Peroxidase-3 (GPX3) Attenuate Inflammation And Oxidant-Mediated Pulmonary Epithelial Injury

Claire Masterson,D Otoole,John G Laffey

(2012)

Cited by3Bibtex

An observational study of the Baska ® mask: a novel supraglottic airway * : Observational study of Baska mask in females

John G Laffey, Leo G Kevin, A Salim, V Alexiev

Anaesthesia, (2012)

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The Role Of Intra-Tracheal Versus Systemic Delivery Of Mesenchymal Stem Cells During Recovery And Resolution Following Ventilator Induced Lung Injury

John G Laffey, Bilal Ansari,Gerard F Curley,D Otoole,M A Hayes

(2012)

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Investigation Of The Role Of NF-ºB In Mediating The Effects Of Metabolic Acidosis On Wound Healing

John G Laffey,D Otoole, Patricia Mchale

(2012)

Bibtex

Ischemia–reperfusion-induced lung injury: Could hypercapnia have a therapeutic role?*

John G Laffey, Bilal Ansari

Critical Care Medicine, (2012)

Cited by3Bibtex

Relationship between growth of food‐spoilage yeast in high‐sugar environments and sensitivity to high‐intensity pulsed UV light irradiation

Jennifer Hayes,John G Laffey,Brian Mcneil,N J Rowan

International Journal of Food Science and Technology, (2012)

Cited by4Bibtex

Relationship between growth of food-spoilage yeast in high-sugar environments and sensitivity to high-intensity pulsed UV light irradiation: Treatment of osmotolerant yeast with PUV

N J Rowan, Brian Mcneil,John G Laffey, Jennifer Hayes

International Journal of Food Science and Technology, (2012)

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Intravenous Allogeneic Human Mesenchymal Stem Cells Restore Alveolar Fluid Clearance In Lungs Rejected For Transplantation In An Ex Vivo Human Lung Perfusion Model

Jason Abbott,David H Mckenna,Xiaohui Fang,Michael A Matthay,Jae W Lee, Daniel F Mcauley,U I Hamid,Gerard F Curley,John G Laffey

(2012)

Bibtex

Initial experience with the Baska mask, a novel supraglottic airway device, in female patients undergoing gynaecologic laparoscopic surgery: 19AP2-1

John G Laffey,A Salim, Jessica M Coyne, V Alexiev

European Journal of Anaesthesiology, (2012)

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Human Mesenchymal Stem Cell-Conditioned Medium May Be Protective In Stretch-Induced Pulmonary Epithelial Injury

Patricia Mchale, Bilal Ansari,D Otoole,Claire Masterson,Gerard F Curley,Mairead Hayes,John G Laffey

(2012)

Bibtex

Individualized patient models combining mathematical models and real-time clinical data

Catherine G Enright,Michael G Madden,Niall Madden,John G Laffey

Journal of Critical Care, (2012)

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