基本信息
浏览量:5
职业迁徙
个人简介
Current interests
Chloroplasts and mitochondria
Why do chloroplasts and mitochondria contain distinct genetic systems to make a small but constant sub-set of their own proteins? I propose that redox control of gene expression explains the function of the genomes of chloroplasts and mitochondria and their retention, in evolution, as extra-nuclear genetic systems. This hypothesis is named “CoRR” for “Co-location for Redox Regulation”. CoRR states that redox regulation of gene expression repays, on its own, the huge cost of maintaining genetic systems in the chloroplasts and mitochondria of eukaryotic cells. For animal mitochondria, this cost includes ageing and death of the individual. Template mitochondria are rescued and granted immortality by means of maternal inheritance and sex. Redox chemistry is thus a key to understanding both cell evolution and biological energy transduction. In my laboratory, Sujith Puthiyaveetil has found the conserved, ancestral, “bacterial” sensor kinase that couples electron transport to chloroplast gene transcription, and whose existence and properties are predicted by CoRR. Numerous experimental predictions flow from this key discovery.
研究兴趣
论文共 258 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Trends in plant scienceno. 11 (2019): 1022-1031
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn